Medical Subject Headings

Last uploaded: January 16, 2025
Id http://purl.bioontology.org/ontology/MESH/D000071187
http://purl.bioontology.org/ontology/MESH/D000071187
Preferred Name

Autophagy-Related Protein 5

Definitions
An autophagy-related protein that functions in AUTOPHAGOSOME biogenesis. It is conjugated to the ATG12 PROTEIN via a process that is similar to UBIQUITINATION and involves the ATG7 PROTEIN and ATG10 enzyme. The ATG12-ATG5 conjugate acts as an E3 UBIQUITIN LIGASE-like enzyme and is required for the localization of ATG8 PROTEINS to AUTOPHAGOSOME vesicle membranes and modification of membrane lipids.
Synonyms
Autophagy Related Protein 5
ATG 5 Protein
Autophagy Related 5 Protein
Apoptosis Specific Protein
Apoptosis-Specific Protein
ATG-5 Protein
ATG5 Protein
Autophagy Protein-5
Autophagy-Related 5 Protein
Autophagy Protein 5
Type http://www.w3.org/2002/07/owl#Class
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