loading...| Preferred Name |
Soluble Guanylyl Cyclase |
|
| Synonyms |
Oxide Receptors, Nitric Nitric Oxide Sensitive Guanylyl Cyclase Oxide Receptor, Nitric Nitric Oxide-Sensitive Guanylyl Cyclase Guanylate Cyclase, Soluble Soluble Guanylate Cyclase Nitric Oxide Receptor Soluble Guanylyl Cyclase, alpha Subunit Cyclase, Soluble Guanylate Guanylyl Cyclase, Soluble Receptor, Nitric Oxide Nitric Oxide Receptors Soluble Guanylyl Cyclase, beta Subunit Cyclase, Soluble Guanylyl |
|
| Definitions |
A mammalian enzyme composed of a heterodimer of alpha and beta subunits. Each subunit consists of four domains; N-terminal HNOX domain, PAS-like domain, a coiled-coil domain, and a C-terminal catalytic domain. All four domains are homologous proteins with a similar conformation of functional domains. Soluble guanylate cyclase catalyzes the formation of cyclic GMP from GTP, and is a key enzyme of the nitric oxide signaling pathway involved in the regulation of a variety of biological and physiological processes in mammals. |
|
| ID |
http://purl.bioontology.org/ontology/MESH/D000071756 |
|
| altLabel |
Oxide Receptors, Nitric Nitric Oxide Sensitive Guanylyl Cyclase Oxide Receptor, Nitric Nitric Oxide-Sensitive Guanylyl Cyclase Guanylate Cyclase, Soluble Soluble Guanylate Cyclase Nitric Oxide Receptor Soluble Guanylyl Cyclase, alpha Subunit Cyclase, Soluble Guanylate Guanylyl Cyclase, Soluble Receptor, Nitric Oxide Nitric Oxide Receptors Soluble Guanylyl Cyclase, beta Subunit Cyclase, Soluble Guanylyl |
|
| AQL |
AD AE AI AN BI BL CF CH CL CS DE DF EC GE HI IM IP ME PD PH PK PO RE SD ST TO TU UL UR |
|
| cui |
C4280028 C4280029 C1097411 |
|
| DC |
1 |
|
| definition |
A mammalian enzyme composed of a heterodimer of alpha and beta subunits. Each subunit consists of four domains; N-terminal HNOX domain, PAS-like domain, a coiled-coil domain, and a C-terminal catalytic domain. All four domains are homologous proteins with a similar conformation of functional domains. Soluble guanylate cyclase catalyzes the formation of cyclic GMP from GTP, and is a key enzyme of the nitric oxide signaling pathway involved in the regulation of a variety of biological and physiological processes in mammals. |
|
| DX |
20170101 |
|
| HN |
2017 (2016) |
|
| Inverse of AQ |
http://purl.bioontology.org/ontology/MESH/Q000097 http://purl.bioontology.org/ontology/MESH/Q000096 http://purl.bioontology.org/ontology/MESH/Q000172 http://purl.bioontology.org/ontology/MESH/Q000627 http://purl.bioontology.org/ontology/MESH/Q000648 http://purl.bioontology.org/ontology/MESH/Q000493 http://purl.bioontology.org/ontology/MESH/Q000494 http://purl.bioontology.org/ontology/MESH/Q000276 http://purl.bioontology.org/ontology/MESH/Q000138 http://purl.bioontology.org/ontology/MESH/Q000134 http://purl.bioontology.org/ontology/MESH/Q000266 http://purl.bioontology.org/ontology/MESH/Q000378 http://purl.bioontology.org/ontology/MESH/Q000008 http://purl.bioontology.org/ontology/MESH/Q000009 http://purl.bioontology.org/ontology/MESH/Q000032 http://purl.bioontology.org/ontology/MESH/Q000037 http://purl.bioontology.org/ontology/MESH/Q000191 http://purl.bioontology.org/ontology/MESH/Q000302 http://purl.bioontology.org/ontology/MESH/Q000145 http://purl.bioontology.org/ontology/MESH/Q000592 http://purl.bioontology.org/ontology/MESH/Q000737 http://purl.bioontology.org/ontology/MESH/Q000502 http://purl.bioontology.org/ontology/MESH/Q000506 http://purl.bioontology.org/ontology/MESH/Q000187 http://purl.bioontology.org/ontology/MESH/Q000235 http://purl.bioontology.org/ontology/MESH/Q000633 http://purl.bioontology.org/ontology/MESH/Q000600 |
|
| Inverse of RB |
EC 4.6.1.2 0 |
|
| Machine permutation |
2017; SOLUBLE GUANYLYL CYCLASE was indexed under GUANYLATE CYCLASE and RECEPTORS, CYTOPLASMIC AND NUCLEAR 2001-2016 |
|
| Mapped from |
http://purl.bioontology.org/ontology/MESH/C000605667 http://purl.bioontology.org/ontology/MESH/C000605665 http://purl.bioontology.org/ontology/MESH/C000605675 http://purl.bioontology.org/ontology/MESH/C000605661 http://purl.bioontology.org/ontology/MESH/C000605660 http://purl.bioontology.org/ontology/MESH/C000605669 http://purl.bioontology.org/ontology/MESH/C000605674 http://purl.bioontology.org/ontology/MESH/C000605670 http://purl.bioontology.org/ontology/MESH/C000605664 http://purl.bioontology.org/ontology/MESH/C000605668 |
|
| MDA |
20160708 |
|
| MMR |
20210521 |
|
| MN |
D08.811.520.650.600.750 D12.776.476.350.500 |
|
| notation |
D000071756 |
|
| prefLabel |
Soluble Guanylyl Cyclase |
|
| RR |
EC 4.6.1.2 |
|
| TERMUI |
T000896699 T000896647 T000896653 T000900878 T000896655 T000900877 T000896654 T000901808 |
|
| TH |
NLM (2017) |
|
| tui |
T116 T126 T192 |
|
| subClassOf |