Medical Subject Headings

Last uploaded: January 16, 2025
Id http://purl.bioontology.org/ontology/MESH/D000073871
http://purl.bioontology.org/ontology/MESH/D000073871
Preferred Name

Triggering Receptor Expressed on Myeloid Cells-1

Definitions
An approximately 230 amino acid membrane glycoprotein characterized by an IMMUNOGLOBULIN V-SET DOMAIN in its N-terminal half. It is expressed by MONOCYTES and NEUTROPHILS in response to INFLAMMATION related to bacterial and fungal infections. It triggers the release of pro-inflammatory CHEMOKINES; CYTOKINES, and expression of cell activation markers and is a critical regulator of SEPTIC SHOCK.
Synonyms
TREM-1 Protein
TREM 1 Protein
CD354 Antigen
Triggering Receptor Expressed on Myeloid Cells 1
Antigen, CD354
Type http://www.w3.org/2002/07/owl#Class
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