Medical Subject Headings

Last uploaded: January 16, 2025
Id http://purl.bioontology.org/ontology/MESH/D000079530
http://purl.bioontology.org/ontology/MESH/D000079530
Preferred Name

Mitochondrial Transmembrane Permeability-Driven Necrosis

Definitions
A form of regulated cell death that is initiated by specific perturbations of the intracellular microenvironment such as severe OXIDATIVE STRESS and cytosolic CALCIUM overload, which result in osmotic breakdown of the MITOCHONDRIAL MEMBRANES.
Synonyms
Mitochondrial Permeability Transition
Mitochondrial Transmembrane Permeability Driven Necrosis
Mitochondrial Transmembrane Permeability Driven Cell Death
Mitochondrial Transmembrane Permeability-Driven Cell Death
Type http://www.w3.org/2002/07/owl#Class
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