Medical Subject Headings

Last uploaded: January 31, 2024
Preferred Name

Biotransformation

Synonyms
Definitions

The chemical alteration of an exogenous substance by or in a biological system. The alteration may inactivate the compound or it may result in the production of an active metabolite of an inactive parent compound. The alterations may be divided into METABOLIC DETOXICATION, PHASE I and METABOLIC DETOXICATION, PHASE II.

ID

http://purl.bioontology.org/ontology/MESH/D001711

AN

restrict to chemical changes of exogenous substances; IM general only; coordinate NIM with specific drug /pharmacokin (IM) or /metab; do not confuse with BIODEGRADATION, ENVIRONMENTAL

AQL

DE GE IM PH RE

cui

C0005576

DC

1

definition

The chemical alteration of an exogenous substance by or in a biological system. The alteration may inactivate the compound or it may result in the production of an active metabolite of an inactive parent compound. The alterations may be divided into METABOLIC DETOXICATION, PHASE I and METABOLIC DETOXICATION, PHASE II.

DX

19700101

HN

70(66)

Inverse of AQ

http://purl.bioontology.org/ontology/MESH/Q000276

http://purl.bioontology.org/ontology/MESH/Q000502

http://purl.bioontology.org/ontology/MESH/Q000187

http://purl.bioontology.org/ontology/MESH/Q000235

http://purl.bioontology.org/ontology/MESH/Q000528

Machine permutation

70

MDA

19990101

MMR

20190701

MN

G03.787.225

G03.171

G07.690.725.225

notation

D001711

prefLabel

Biotransformation

TERMUI

T004973

TH

NLM (1966)

tui

T040

subClassOf

http://purl.bioontology.org/ontology/MESH/D008660

http://purl.bioontology.org/ontology/MESH/D010599

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