Medical Subject Headings

Last uploaded: January 16, 2025
Id http://purl.bioontology.org/ontology/MESH/D002301
http://purl.bioontology.org/ontology/MESH/D002301
Preferred Name

Cardiac Glycosides

Definitions
Cyclopentanophenanthrenes with a 5- or 6-membered lactone ring attached at the 17-position and SUGARS attached at the 3-position. Plants they come from have long been used in congestive heart failure. They increase the force of cardiac contraction without significantly affecting other parameters, but are very toxic at larger doses. Their mechanism of action usually involves inhibition of the NA(+)-K(+)-EXCHANGING ATPASE and they are often used in cell biological studies for that purpose.
Synonyms
Cardiotonic Steroid
Cardiotonic Steroids
Glycosides, Cardiac
Steroids, Cardiotonic
Steroid, Cardiotonic
Cardiac Glycoside
Glycoside, Cardiac
Type http://www.w3.org/2002/07/owl#Class
Delete Subject Author Type Created
No notes to display
  • Problem retrieving properties:

Notes

Filter:
Add NCBO Web Widgets to your site for MESH
Widget type Widget demonstration
Jump To

Type a class name from MESH and jump to it in BioPortal

Get code
Form Autocomplete

Fill your form fields with classes from MESH

Get code
Example 1 (start typing the class name to get its full URI)

Example 2 (get the ID for a class)

Example 3 (get the preferred name for a class)
Visualization

Display a visualization for a given class in MESH

Get code
Tree Widget

Display a class tree with a search field for MESH

Get code