Preferred Name |
Drug Tolerance |
|
Synonyms |
Tolerance, Drug Drug Tolerances |
|
Definitions |
Progressive diminution of the susceptibility of a human or animal to the effects of a drug, resulting from its continued administration. It should be differentiated from DRUG RESISTANCE wherein an organism, disease, or tissue fails to respond to the intended effectiveness of a chemical or drug. It should also be differentiated from MAXIMUM TOLERATED DOSE and NO-OBSERVED-ADVERSE-EFFECT LEVEL. |
|
ID |
http://purl.bioontology.org/ontology/MESH/D004361 |
|
altLabel |
Tolerance, Drug Tolerances, Drug Drug Tolerances |
|
AN |
differentiate from DRUG RESISTANCE; not for tolerability ( = drug /adv eff): Manual 28.19 |
|
AQL |
EH GE IM PH RE |
|
cui |
C0013220 |
|
DC |
1 |
|
definition |
Progressive diminution of the susceptibility of a human or animal to the effects of a drug, resulting from its continued administration. It should be differentiated from DRUG RESISTANCE wherein an organism, disease, or tissue fails to respond to the intended effectiveness of a chemical or drug. It should also be differentiated from MAXIMUM TOLERATED DOSE and NO-OBSERVED-ADVERSE-EFFECT LEVEL. |
|
DX |
19660101 |
|
Inverse of AQ |
http://purl.bioontology.org/ontology/MESH/Q000276 http://purl.bioontology.org/ontology/MESH/Q000502 http://purl.bioontology.org/ontology/MESH/Q000235 |
|
MDA |
19990101 |
|
MMR |
20150629 |
|
MN |
G07.690.773.992 |
|
notation |
D004361 |
|
prefLabel |
Drug Tolerance |
|
TERMUI |
T013321 |
|
TH |
NLM (1966) |
|
tui |
T033 |
|
subClassOf |