Medical Subject Headings

Last uploaded: January 31, 2024
Preferred Name

Drug Tolerance

Synonyms

Tolerance, Drug

Drug Tolerances

Definitions

Progressive diminution of the susceptibility of a human or animal to the effects of a drug, resulting from its continued administration. It should be differentiated from DRUG RESISTANCE wherein an organism, disease, or tissue fails to respond to the intended effectiveness of a chemical or drug. It should also be differentiated from MAXIMUM TOLERATED DOSE and NO-OBSERVED-ADVERSE-EFFECT LEVEL.

ID

http://purl.bioontology.org/ontology/MESH/D004361

altLabel

Tolerance, Drug

Tolerances, Drug

Drug Tolerances

AN

differentiate from DRUG RESISTANCE; not for tolerability ( = drug /adv eff): Manual 28.19

AQL

EH GE IM PH RE

cui

C0013220

DC

1

definition

Progressive diminution of the susceptibility of a human or animal to the effects of a drug, resulting from its continued administration. It should be differentiated from DRUG RESISTANCE wherein an organism, disease, or tissue fails to respond to the intended effectiveness of a chemical or drug. It should also be differentiated from MAXIMUM TOLERATED DOSE and NO-OBSERVED-ADVERSE-EFFECT LEVEL.

DX

19660101

Inverse of AQ

http://purl.bioontology.org/ontology/MESH/Q000276

http://purl.bioontology.org/ontology/MESH/Q000502

http://purl.bioontology.org/ontology/MESH/Q000235

http://purl.bioontology.org/ontology/MESH/Q000208

http://purl.bioontology.org/ontology/MESH/Q000528

MDA

19990101

MMR

20150629

MN

G07.690.773.992

notation

D004361

prefLabel

Drug Tolerance

TERMUI

T013321

TH

NLM (1966)

tui

T033

subClassOf

http://purl.bioontology.org/ontology/MESH/D000069437

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http://purl.bioontology.org/ontology/SNOMEDCT/228432001 SNOMEDCT CUI
http://purl.bioontology.org/ontology/SNMI/DF-10300 SNMI CUI
http://purl.bioontology.org/ontology/MEDDRA/10052804 MEDDRA CUI
http://purl.bioontology.org/ontology/MDRFRE/10052804 MDRFRE CUI
http://purl.bioontology.org/ontology/CSP/0964-2204 CRISP CUI
http://purl.bioontology.org/ontology/SCTSPA/88320008 SCTSPA CUI
http://purl.bioontology.org/ontology/MDRGER/10052804 MDRGER CUI
http://purl.bioontology.org/ontology/SNOMEDCT/88320008 SNOMEDCT CUI
http://purl.bioontology.org/ontology/MSHFRE/D004361 MSHFRE CUI
http://purl.bioontology.org/ontology/RCD/Ub0nr RCD CUI
http://purl.bioontology.org/ontology/SCTSPA/228432001 SCTSPA CUI
http://purl.jp/bio/4/id/200906026644812010 IOBC LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/228432001 SNOMEDCT LOOM
http://purl.bioontology.org/ontology/MEDDRA/10052804 MEDDRA LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D004361 RH-MESH LOOM
http://id.nlm.nih.gov/mesh/D004361 MDM LOOM
http://www.co-ode.org/ontologies/galen#DrugTolerance GALEN LOOM
http://purl.bioontology.org/ontology/CSP/0964-2204 CRISP LOOM
http://ontology.apa.org/apaonto/termsonlyOUT%20(5).owl#Drug_Tolerance APAONTO LOOM
http://www.limics.fr/ontologies/ontoparonmed#ToleranceAuxMedicaments ONTOPARON LOOM
http://purl.bioontology.org/ontology/RCTV2/13cG.00 RCTV2 LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C21130 NCIT LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/88320008 SNOMEDCT LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#G07.700.680.260 RH-MESH LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#4156 OCHV LOOM
http://purl.obolibrary.org/obo/OMIT_0005617 OMIT LOOM
http://purl.bioontology.org/ontology/RCD/Ub0nr RCD LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0013220 OCHV LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#G07.690.812.260 RH-MESH LOOM