loading...| Preferred Name |
Encephalomyelitis, Autoimmune, Experimental |
|
| Synonyms |
Autoimmune Encephalomyelitis, Experimental |
|
| Definitions |
An experimental animal model for central nervous system demyelinating disease. Inoculation with a white matter emulsion combined with FREUND'S ADJUVANT, myelin basic protein, or purified central myelin triggers a T cell-mediated immune response directed towards central myelin. The pathologic features are similar to MULTIPLE SCLEROSIS, including perivascular and periventricular foci of inflammation and demyelination. Subpial demyelination underlying meningeal infiltrations also occurs, which is also a feature of ENCEPHALOMYELITIS, ACUTE DISSEMINATED. Passive immunization with T-cells from an afflicted animal to a normal animal also induces this condition. (From Immunol Res 1998;17(1-2):217-27; Raine CS, Textbook of Neuropathology, 2nd ed, p604-5) |
|
| ID |
http://purl.bioontology.org/ontology/MESH/D004681 |
|
| altLabel |
Autoimmune Encephalomyelitis, Experimental Experimental Encephalomyelitis, Autoimmune Allergic Encephalomyelitis Experimental Allergic Encephalomyelitides Encephalomyelitis, Experimental Autoimmune Encephalomyelitis, Autoimmune Experimental Encephalomyelitis, Allergic Experimental Autoimmune Encephalomyelitis Autoimmune Experimental Encephalomyelitis Encephalomyelitis, Experimental Allergic Allergic Encephalomyelitis, Experimental Experimental Allergic Encephalomyelitis |
|
| AN |
coordinate with specific demyelinating disease if pertinent |
|
| AQL |
BL CF CI CL CO DG DH DI DT EC EH EM EN EP ET GE HI IM ME MI MO NU PA PC PP PS PX RH RT SU TH UR VE VI |
|
| cui |
C5574734 C0014072 |
|
| DC |
1 |
|
| definition |
An experimental animal model for central nervous system demyelinating disease. Inoculation with a white matter emulsion combined with FREUND'S ADJUVANT, myelin basic protein, or purified central myelin triggers a T cell-mediated immune response directed towards central myelin. The pathologic features are similar to MULTIPLE SCLEROSIS, including perivascular and periventricular foci of inflammation and demyelination. Subpial demyelination underlying meningeal infiltrations also occurs, which is also a feature of ENCEPHALOMYELITIS, ACUTE DISSEMINATED. Passive immunization with T-cells from an afflicted animal to a normal animal also induces this condition. (From Immunol Res 1998;17(1-2):217-27; Raine CS, Textbook of Neuropathology, 2nd ed, p604-5) |
|
| DX |
19660101 |
|
| HN |
2005 (1964) |
|
| Inverse of AQ |
http://purl.bioontology.org/ontology/MESH/Q000097 http://purl.bioontology.org/ontology/MESH/Q000178 http://purl.bioontology.org/ontology/MESH/Q000175 http://purl.bioontology.org/ontology/MESH/Q000628 http://purl.bioontology.org/ontology/MESH/Q000276 http://purl.bioontology.org/ontology/MESH/Q000134 http://purl.bioontology.org/ontology/MESH/Q000139 http://purl.bioontology.org/ontology/MESH/Q000266 http://purl.bioontology.org/ontology/MESH/Q000378 http://purl.bioontology.org/ontology/MESH/Q000517 http://purl.bioontology.org/ontology/MESH/Q000662 http://purl.bioontology.org/ontology/MESH/Q000469 http://purl.bioontology.org/ontology/MESH/Q000150 http://purl.bioontology.org/ontology/MESH/Q000821 http://purl.bioontology.org/ontology/MESH/Q000191 http://purl.bioontology.org/ontology/MESH/Q000196 http://purl.bioontology.org/ontology/MESH/Q000473 http://purl.bioontology.org/ontology/MESH/Q000145 http://purl.bioontology.org/ontology/MESH/Q000382 http://purl.bioontology.org/ontology/MESH/Q000451 http://purl.bioontology.org/ontology/MESH/Q000453 http://purl.bioontology.org/ontology/MESH/Q000534 http://purl.bioontology.org/ontology/MESH/Q000532 http://purl.bioontology.org/ontology/MESH/Q000503 http://purl.bioontology.org/ontology/MESH/Q000188 http://purl.bioontology.org/ontology/MESH/Q000235 http://purl.bioontology.org/ontology/MESH/Q000201 http://purl.bioontology.org/ontology/MESH/Q000209 http://purl.bioontology.org/ontology/MESH/Q000208 http://purl.bioontology.org/ontology/MESH/Q000601 http://purl.bioontology.org/ontology/MESH/Q000000981 http://purl.bioontology.org/ontology/MESH/Q000652 |
|
| Machine permutation |
2005; see ENCEPHALOMYELITIS, EXPERIMENTAL AUTOIMMUNE 2000-2004, see ENCEPHALOMYELITIS, ALLERGIC 1964-1999 |
|
| MDA |
19990101 |
|
| MMR |
20220413 |
|
| MN |
C20.111.258.625.300 C10.228.140.695.562.250 C10.114.703.300 E05.598.500.500.500 C10.314.350.250 |
|
| notation |
D004681 |
|
| prefLabel |
Encephalomyelitis, Autoimmune, Experimental |
|
| TERMUI |
T365221 T014338 T014344 T014346 T014339 T014347 T014340 T014341 T014345 |
|
| TH |
NLM (1996) NLM (2000) NLM (1995) NLM (1992) NLM (1964) ORD (2010) |
|
| tui |
T047 T050 |
|
| subClassOf |