Medical Subject Headings

Last uploaded: January 16, 2025
Id http://purl.bioontology.org/ontology/MESH/D004815
http://purl.bioontology.org/ontology/MESH/D004815
Preferred Name

Epidermal Growth Factor

Definitions
A 6-kDa polypeptide growth factor initially discovered in mouse submaxillary glands. Human epidermal growth factor was originally isolated from urine based on its ability to inhibit gastric secretion and called urogastrone. Epidermal growth factor exerts a wide variety of biological effects including the promotion of proliferation and differentiation of mesenchymal and EPITHELIAL CELLS. It is synthesized as a transmembrane protein which can be cleaved to release a soluble active form.
Synonyms
Human Urinary Gastric Inhibitor
beta-Urogastrone
Growth Factor, Epidermal
Epidermal growth factor
Growth Factor-Urogastrone, Epidermal
beta Urogastrone
EGF
Epidermal Growth Factor-Urogastrone
Urogastrone
Type http://www.w3.org/2002/07/owl#Class
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