Medical Subject Headings

Last uploaded: January 16, 2025
Id http://purl.bioontology.org/ontology/MESH/D007328
http://purl.bioontology.org/ontology/MESH/D007328
Preferred Name

Insulin

Definitions
A 51-amino acid pancreatic hormone that plays a major role in the regulation of glucose metabolism, directly by suppressing endogenous glucose production (GLYCOGENOLYSIS; GLUCONEOGENESIS) and indirectly by suppressing GLUCAGON secretion and LIPOLYSIS. Native insulin is a globular protein comprised of a zinc-coordinated hexamer. Each insulin monomer containing two chains, A (21 residues) and B (30 residues), linked by two disulfide bonds. Insulin is used as a drug to control insulin-dependent diabetes mellitus (DIABETES MELLITUS, TYPE 1).
Synonyms
Sodium Insulin
Soluble Insulin
Insulin, Sodium
Insulin A Chain
Insulin, Soluble
Insulin, Regular
Iletin
Novolin
Regular Insulin
Insulin B Chain
Chain, Insulin B
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Type http://www.w3.org/2002/07/owl#Class
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