Medical Subject Headings

Last uploaded: January 16, 2025
Id http://purl.bioontology.org/ontology/MESH/D007515
http://purl.bioontology.org/ontology/MESH/D007515
Preferred Name

Islets of Langerhans

Definitions
Irregular microscopic structures consisting of cords of endocrine cells that are scattered throughout the PANCREAS among the exocrine acini. Each islet is surrounded by connective tissue fibers and penetrated by a network of capillaries. There are four major cell types. The most abundant beta cells (50-80%) secrete INSULIN. Alpha cells (5-20%) secrete GLUCAGON. PP cells (10-35%) secrete PANCREATIC POLYPEPTIDE. Delta cells (~5%) secrete SOMATOSTATIN.
Synonyms
Pancreatic Islets
Nesidioblasts
Islet, Pancreatic
Cells, Islet
Endocrine Pancreas
Nesidioblast
Islets, Pancreatic
Islands of Langerhans
Pancreas, Endocrine
Pancreatic Islet
Langerhans Islets
Langerhans Islands
Cell, Islet
Islet Cell
Islet Cells
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Type http://www.w3.org/2002/07/owl#Class
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