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Medical Subject Headings
Last uploaded:
January 16, 2025
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| Id | http://purl.bioontology.org/ontology/MESH/D009691
http://purl.bioontology.org/ontology/MESH/D009691
|
|---|---|
| Preferred Name | Nucleic Acid Denaturation |
| Definitions |
Disruption of the secondary structure of nucleic acids by heat, extreme pH or chemical treatment. Double strand DNA is melted by dissociation of the non-covalent hydrogen bonds and hydrophobic interactions. Denatured DNA appears to be a single-stranded flexible structure. The effects of denaturation on RNA are similar though less pronounced and largely reversible.
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| Synonyms |
Acid Denaturation, Nucleic
Nucleic Acid Denaturations
DNA Melting
Denaturation, Nucleic Acid
DNA Denaturation
Denaturation, DNA
Denaturation, RNA
RNA Denaturation
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | Disruption of the secondary structure of nucleic acids by heat, extreme pH or chemical treatment. Double strand DNA is melted by dissociation of the non-covalent hydrogen bonds and hydrophobic interactions. Denatured DNA appears to be a single-stranded flexible structure. The effects of denaturation on RNA are similar though less pronounced and largely reversible. |
|---|---|
| altLabel |
Acid Denaturation, Nucleic
Nucleic Acid Denaturations
DNA Melting
Denaturation, Nucleic Acid
DNA Denaturation
Denaturation, DNA
Denaturation, RNA
RNA Denaturation
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| prefLabel | Nucleic Acid Denaturation
|
| TH |
NLM (1967)
NLM (2006)
|
| notation | D009691
|
| DX | 19700101
|
| Machine permutation | 70
|
| MN |
E05.393.640
G05.627
G02.111.603
|
| FX | D020871
|
| MMR | 20160617
|
| AQL | DE GE PD RE
|
| HN | 70(67)
|
| subClassOf | |
| Semantic type UMLS property | |
| DC | 1
|
| MDA | 19990101
|
| Inverse of RO | |
| type | |
| tui | T070
|
| cui |
C1720789
C1720790
C0028600
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| AN | IM general only; coord NIM with DNA or RNA or specific (IM)
|
| Inverse of AQ | |
| TERMUI |
T028819
T674637
T674636
T674638
|
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