loading...| Preferred Name |
Bulbar Palsy, Progressive |
|
| Synonyms |
Syndrome, Fazio-Londe |
|
| Definitions |
A motor neuron disease marked by progressive weakness of the muscles innervated by cranial nerves of the lower brain stem. Clinical manifestations include dysarthria, dysphagia, facial weakness, tongue weakness, and fasciculations of the tongue and facial muscles. The adult form of the disease is marked initially by bulbar weakness which progresses to involve motor neurons throughout the neuroaxis. Eventually this condition may become indistinguishable from AMYOTROPHIC LATERAL SCLEROSIS. Fazio-Londe syndrome is an inherited form of this illness which occurs in children and young adults. (Adams et al., Principles of Neurology, 6th ed, p1091; Brain 1992 Dec;115(Pt 6):1889-1900) |
|
| ID |
http://purl.bioontology.org/ontology/MESH/D010244 |
|
| altLabel |
Syndrome, Fazio-Londe Disease, Fazio-Londe's Fazio Londe's Disease Progressive Bulbar Palsies Palsy, Bulbar Bulbar Palsies, Progressive Fazio-Londe's Disease Paralysis, Bulbar Bulbar Paralyses Childhood Progressive Bulbar Palsy Fazio Londe's Syndrome Fazio Londe Syndrome Syndrome, Fazio-Londe's Fazio-Londe Disease Fazio-Londe Syndrome Progressive Bulbar Palsy of Childhood Bulbar Paralysis Palsies, Progressive Bulbar Bulbar Palsy, Progressive, Of Childhood Bulbar Palsy Palsies, Bulbar Bulbar Palsies Fazio-Londe's Syndrome Palsy, Progressive Bulbar Fazio Londe Disease Disease, Fazio-Londe |
|
| AQL |
BL CF CI CL CN CO DG DH DI DT EC EH EM EN EP ET GE HI IM ME MI MO NU PA PC PP PS PX RH RT SU TH UR VE VI |
|
| cui |
C0393540 C4082299 C0030442 |
|
| DC |
1 |
|
| definition |
A motor neuron disease marked by progressive weakness of the muscles innervated by cranial nerves of the lower brain stem. Clinical manifestations include dysarthria, dysphagia, facial weakness, tongue weakness, and fasciculations of the tongue and facial muscles. The adult form of the disease is marked initially by bulbar weakness which progresses to involve motor neurons throughout the neuroaxis. Eventually this condition may become indistinguishable from AMYOTROPHIC LATERAL SCLEROSIS. Fazio-Londe syndrome is an inherited form of this illness which occurs in children and young adults. (Adams et al., Principles of Neurology, 6th ed, p1091; Brain 1992 Dec;115(Pt 6):1889-1900) |
|
| DX |
20000101 |
|
| HN |
2000(1966) |
|
| Inverse of AQ |
http://purl.bioontology.org/ontology/MESH/Q000097 http://purl.bioontology.org/ontology/MESH/Q000178 http://purl.bioontology.org/ontology/MESH/Q000175 http://purl.bioontology.org/ontology/MESH/Q000628 http://purl.bioontology.org/ontology/MESH/Q000276 http://purl.bioontology.org/ontology/MESH/Q000134 http://purl.bioontology.org/ontology/MESH/Q000139 http://purl.bioontology.org/ontology/MESH/Q000266 http://purl.bioontology.org/ontology/MESH/Q000378 http://purl.bioontology.org/ontology/MESH/Q000517 http://purl.bioontology.org/ontology/MESH/Q000662 http://purl.bioontology.org/ontology/MESH/Q000469 http://purl.bioontology.org/ontology/MESH/Q000151 http://purl.bioontology.org/ontology/MESH/Q000150 http://purl.bioontology.org/ontology/MESH/Q000821 http://purl.bioontology.org/ontology/MESH/Q000191 http://purl.bioontology.org/ontology/MESH/Q000196 http://purl.bioontology.org/ontology/MESH/Q000473 http://purl.bioontology.org/ontology/MESH/Q000145 http://purl.bioontology.org/ontology/MESH/Q000382 http://purl.bioontology.org/ontology/MESH/Q000451 http://purl.bioontology.org/ontology/MESH/Q000453 http://purl.bioontology.org/ontology/MESH/Q000534 http://purl.bioontology.org/ontology/MESH/Q000532 http://purl.bioontology.org/ontology/MESH/Q000503 http://purl.bioontology.org/ontology/MESH/Q000188 http://purl.bioontology.org/ontology/MESH/Q000235 http://purl.bioontology.org/ontology/MESH/Q000201 http://purl.bioontology.org/ontology/MESH/Q000209 http://purl.bioontology.org/ontology/MESH/Q000208 http://purl.bioontology.org/ontology/MESH/Q000601 http://purl.bioontology.org/ontology/MESH/Q000000981 http://purl.bioontology.org/ontology/MESH/Q000652 |
|
| Machine permutation |
2000; see PARALYSIS, BULBAR 1966-1999 |
|
| Mapped from | ||
| MDA |
19990101 |
|
| MMR |
20220714 |
|
| MN |
C10.574.562.300 C10.668.467.300 |
|
| notation |
D010244 |
|
| prefLabel |
Bulbar Palsy, Progressive |
|
| TERMUI |
T372094 T365782 T001115762 T001114240 T030275 T030274 T001114241 T372095 T812345 T001115763 |
|
| TH |
OMIM (2013) NLM (2000) NLM (2023) NLM (1966) UNK (19XX) |
|
| tui |
T047 |
|
| subClassOf |