loading...| Preferred Name |
Quinine |
|
| Synonyms |
Bisulfate, Quinine |
|
| Definitions |
An alkaloid derived from the bark of the cinchona tree. It is used as an antimalarial drug, and is the active ingredient in extracts of the cinchona that have been used for that purpose since before 1633. Quinine is also a mild antipyretic and analgesic and has been used in common cold preparations for that purpose. It was used commonly and as a bitter and flavoring agent, and is still useful for the treatment of babesiosis. Quinine is also useful in some muscular disorders, especially nocturnal leg cramps and myotonia congenita, because of its direct effects on muscle membrane and sodium channels. The mechanisms of its antimalarial effects are not well understood. |
|
| ID |
http://purl.bioontology.org/ontology/MESH/D011803 |
|
| altLabel |
Bisulfate, Quinine Cinchonan-9-ol, 6'-methoxy-, (8alpha,9R)- Sulfate, Quinine Quinine-Odan Quinbisul Surquina Hydrochloride, Quinine Quinimax Quinamm Sulphate, Quinine Quinbisan Quinsul Myoquin Quinine Bisulfate Quinine Lafran Quinine Sulfate Quinoctal Quinson Biquinate Quinine Hydrochloride Legatrim Strema Quinine Sulphate Quindan |
|
| AN |
/biosyn permitted if by plant |
|
| AQL |
AA AD AE AG AI AN BI BL CF CH CL CS EC GE HI IM IP ME PD PK PO RE SD ST TO TU UR |
|
| cui |
C1564028 C1564025 C1564024 C0034416 C1564026 C0034420 C1564030 C1564027 C1564029 C0034422 C0034409 C0034417 C1564023 C1564031 C0722963 C1564022 C0034421 |
|
| DC |
1 |
|
| definition |
An alkaloid derived from the bark of the cinchona tree. It is used as an antimalarial drug, and is the active ingredient in extracts of the cinchona that have been used for that purpose since before 1633. Quinine is also a mild antipyretic and analgesic and has been used in common cold preparations for that purpose. It was used commonly and as a bitter and flavoring agent, and is still useful for the treatment of babesiosis. Quinine is also useful in some muscular disorders, especially nocturnal leg cramps and myotonia congenita, because of its direct effects on muscle membrane and sodium channels. The mechanisms of its antimalarial effects are not well understood. |
|
| DX |
19660101 |
|
| Inverse of AQ |
http://purl.bioontology.org/ontology/MESH/Q000097 http://purl.bioontology.org/ontology/MESH/Q000096 http://purl.bioontology.org/ontology/MESH/Q000627 http://purl.bioontology.org/ontology/MESH/Q000493 http://purl.bioontology.org/ontology/MESH/Q000494 http://purl.bioontology.org/ontology/MESH/Q000276 http://purl.bioontology.org/ontology/MESH/Q000138 http://purl.bioontology.org/ontology/MESH/Q000134 http://purl.bioontology.org/ontology/MESH/Q000266 http://purl.bioontology.org/ontology/MESH/Q000378 http://purl.bioontology.org/ontology/MESH/Q000008 http://purl.bioontology.org/ontology/MESH/Q000009 http://purl.bioontology.org/ontology/MESH/Q000031 http://purl.bioontology.org/ontology/MESH/Q000032 http://purl.bioontology.org/ontology/MESH/Q000037 http://purl.bioontology.org/ontology/MESH/Q000191 http://purl.bioontology.org/ontology/MESH/Q000302 http://purl.bioontology.org/ontology/MESH/Q000145 http://purl.bioontology.org/ontology/MESH/Q000592 http://purl.bioontology.org/ontology/MESH/Q000737 http://purl.bioontology.org/ontology/MESH/Q000819 http://purl.bioontology.org/ontology/MESH/Q000506 http://purl.bioontology.org/ontology/MESH/Q000235 http://purl.bioontology.org/ontology/MESH/Q000633 http://purl.bioontology.org/ontology/MESH/Q000600 |
|
| Inverse of RB |
M201HC068W A7V27PHC7A KF7Z0E0Q2B 0 711S8Y0T33 |
|
| isa |
http://purl.bioontology.org/ontology/MESH/D000962 |
|
| LT |
TRD |
|
| Mapped from |
http://purl.bioontology.org/ontology/MESH/C017303 http://purl.bioontology.org/ontology/MESH/C043568 http://purl.bioontology.org/ontology/MESH/C070445 http://purl.bioontology.org/ontology/MESH/C086286 http://purl.bioontology.org/ontology/MESH/C016184 http://purl.bioontology.org/ontology/MESH/C000591636 http://purl.bioontology.org/ontology/MESH/C542879 http://purl.bioontology.org/ontology/MESH/C541326 http://purl.bioontology.org/ontology/MESH/C029819 http://purl.bioontology.org/ontology/MESH/C029818 http://purl.bioontology.org/ontology/MESH/C009682 http://purl.bioontology.org/ontology/MESH/C518834 http://purl.bioontology.org/ontology/MESH/C572719 http://purl.bioontology.org/ontology/MESH/C025678 http://purl.bioontology.org/ontology/MESH/C009499 http://purl.bioontology.org/ontology/MESH/C000609819 http://purl.bioontology.org/ontology/MESH/C061791 http://purl.bioontology.org/ontology/MESH/C029822 http://purl.bioontology.org/ontology/MESH/C029821 http://purl.bioontology.org/ontology/MESH/C029820 http://purl.bioontology.org/ontology/MESH/C496815 http://purl.bioontology.org/ontology/MESH/C060496 |
|
| MDA |
19990101 |
|
| MMR |
20170524 |
|
| MN |
D03.605.687.762 D03.633.100.810.762 D03.132.206.719 |
|
| notation |
D011803 |
|
| PA |
D018712 D000962 D009125 |
|
| prefLabel |
Quinine |
|
| RR |
M201HC068W KF7Z0E0Q2B 130-95-0 (Quinine) 711S8Y0T33 |
|
| TERMUI |
T616787 T034864 T034858 T034859 T616779 T616776 T616785 T616778 T616772 T616780 T616789 T616766 T616770 T034861 T034860 T616783 T034863 T616774 T034862 T616768 |
|
| TH |
US NLM (1966) CA FDA SRS (2014) UNK (19XX) AU USP (19XX) FR |
|
| tui |
T109 T121 |
|
| subClassOf |
http://purl.bioontology.org/ontology/MESH/D002930 |