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Medical Subject Headings

Last uploaded: January 16, 2025
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Id http://purl.bioontology.org/ontology/MESH/D012083
http://purl.bioontology.org/ontology/MESH/D012083
Preferred Name

Renin
Definitions
A highly specific (Leu-Leu) endopeptidase that generates ANGIOTENSIN I from its precursor ANGIOTENSINOGEN, leading to a cascade of reactions which elevate BLOOD PRESSURE and increase sodium retention by the kidney in the RENIN-ANGIOTENSIN SYSTEM. The enzyme was formerly listed as EC 3.4.99.19.
Synonyms
Angiotensin-Forming Enzyme
Pre-Prorenin
Renin, Big
Renin, Inactive
Angiotensinogenase
Angiotensin Forming Enzyme
Preprorenin
Pre Prorenin
Big Renin
Cryorenin
Inactive Renin
Prorenin
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Type http://www.w3.org/2002/07/owl#Class

All Properties

definition

A highly specific (Leu-Leu) endopeptidase that generates ANGIOTENSIN I from its precursor ANGIOTENSINOGEN, leading to a cascade of reactions which elevate BLOOD PRESSURE and increase sodium retention by the kidney in the RENIN-ANGIOTENSIN SYSTEM. The enzyme was formerly listed as EC 3.4.99.19.
altLabel
Angiotensin-Forming Enzyme
Pre-Prorenin
Renin, Big
Renin, Inactive
Angiotensinogenase
Angiotensin Forming Enzyme
Preprorenin
Pre Prorenin
Big Renin
Cryorenin
Inactive Renin
Prorenin
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prefLabel
Renin
TH
NLM (2004)
NLM (1991)
NLM (1966)
notation
D012083
RR
80965-96-4 (CRN)
DX
19630101
Machine permutation
1963; PRORENIN was listed under ENZYME PRECUSORS & RENIN 1977-2003; PREPRORENIN was listed under ENZYME PRECUSORS & RENIN 1980-2003
MN
D08.811.277.656.300.048.780
D08.811.277.656.074.500.780
D08.811.277.656.837.750
MMR
20090706
Mapped from
AQL
AD AE AI AN BI BL CF CH CL CS DE DF EC GE HI IM IP ME PD PH PK PO RE SD ST TO TU UL UR
HN
1963; for PRORENIN use RENIN (NM) 1977-2003, for PREPRORENIN use RENIN (NM) 1980-2003
subClassOf
Semantic type UMLS property
Inverse of RB
EC 3.4.23.-
EC 3.4.23.15
DC
1
MDA
19990101
Inverse of RO
type
tui
T116
T126
T123
T121
cui
C0035094
C0071937
C0072249
AN
do not confuse with RENNIN see CHYMOSIN
Inverse of AQ
http://purl.bioontology.org/ontology/MESH/Q000097
http://purl.bioontology.org/ontology/MESH/Q000096
http://purl.bioontology.org/ontology/MESH/Q000172
http://purl.bioontology.org/ontology/MESH/Q000627
http://purl.bioontology.org/ontology/MESH/Q000648
http://purl.bioontology.org/ontology/MESH/Q000493
http://purl.bioontology.org/ontology/MESH/Q000494
http://purl.bioontology.org/ontology/MESH/Q000276
http://purl.bioontology.org/ontology/MESH/Q000138
http://purl.bioontology.org/ontology/MESH/Q000134
http://purl.bioontology.org/ontology/MESH/Q000266
http://purl.bioontology.org/ontology/MESH/Q000378
http://purl.bioontology.org/ontology/MESH/Q000008
http://purl.bioontology.org/ontology/MESH/Q000009
http://purl.bioontology.org/ontology/MESH/Q000032
http://purl.bioontology.org/ontology/MESH/Q000037
http://purl.bioontology.org/ontology/MESH/Q000191
http://purl.bioontology.org/ontology/MESH/Q000302
http://purl.bioontology.org/ontology/MESH/Q000145
http://purl.bioontology.org/ontology/MESH/Q000592
http://purl.bioontology.org/ontology/MESH/Q000737
http://purl.bioontology.org/ontology/MESH/Q000502
http://purl.bioontology.org/ontology/MESH/Q000506
http://purl.bioontology.org/ontology/MESH/Q000187
http://purl.bioontology.org/ontology/MESH/Q000235
http://purl.bioontology.org/ontology/MESH/Q000633
http://purl.bioontology.org/ontology/MESH/Q000600
http://purl.bioontology.org/ontology/MESH/Q000652
http://purl.bioontology.org/ontology/MESH/Q000528
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TERMUI
T112819
T091611
T091609
T112818
T035937
T091610
T091608
T035936
T035938
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