loading...| Preferred Name |
Retinoblastoma |
|
| Synonyms |
Glioblastomas, Retinal |
|
| Definitions |
A malignant tumor arising from the nuclear layer of the retina that is the most common primary tumor of the eye in children. The tumor tends to occur in early childhood or infancy and may be present at birth. The majority are sporadic, but the condition may be transmitted as an autosomal dominant trait. Histologic features include dense cellularity, small round polygonal cells, and areas of calcification and necrosis. An abnormal pupil reflex (leukokoria); NYSTAGMUS, PATHOLOGIC; STRABISMUS; and visual loss represent common clinical characteristics of this condition. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, p2104) |
|
| ID |
http://purl.bioontology.org/ontology/MESH/D012175 |
|
| altLabel |
Glioblastomas, Retinal Retinal Gliomas Sporadic Retinoblastoma Familial Retinoblastoma Retinoblastoma, Hereditary Retinal Neuroblastoma Hereditary Retinoblastomas Retinal Glioma Retinoblastomas Retinoblastoma Eye Cancers Gliomas, Retinal Cancer, Retinoblastoma Eye Retinal Glioblastoma Retinoblastomas, Familial Eye Cancer, Retinoblastoma Familial Retinoblastomas Retinoblastoma, Sporadic Neuroblastoma, Retinal Eye Cancers, Retinoblastoma Cancers, Retinoblastoma Eye Retinal Neuroblastomas Sporadic Retinoblastomas Retinoblastomas, Hereditary Retinoblastoma Eye Cancer Neuroblastomas, Retinal Hereditary Retinoblastoma Glioma, Retinal Retinoblastomas, Sporadic Retinoblastoma, Familial Glioblastoma, Retinal Retinal Glioblastomas |
|
| AN |
coordinate IM with RETINAL NEOPLASMS (IM); /genetics: consider also GENES, RETINOBLASTOMA |
|
| AQL |
BL BS CF CH CI CL CN CO DG DH DI DT EC EH EM EN EP ET GE HI IM ME MI MO NU PA PC PP PS PX RH RT SC SU TH UL UR VE VI |
|
| cui |
C5779886 C5779887 C0751484 C0751483 C5779888 C0035335 |
|
| DC |
1 |
|
| definition |
A malignant tumor arising from the nuclear layer of the retina that is the most common primary tumor of the eye in children. The tumor tends to occur in early childhood or infancy and may be present at birth. The majority are sporadic, but the condition may be transmitted as an autosomal dominant trait. Histologic features include dense cellularity, small round polygonal cells, and areas of calcification and necrosis. An abnormal pupil reflex (leukokoria); NYSTAGMUS, PATHOLOGIC; STRABISMUS; and visual loss represent common clinical characteristics of this condition. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, p2104) |
|
| DX |
19660101 |
|
| FX |
D016161 |
|
| Inverse of AQ |
http://purl.bioontology.org/ontology/MESH/Q000097 http://purl.bioontology.org/ontology/MESH/Q000098 http://purl.bioontology.org/ontology/MESH/Q000178 http://purl.bioontology.org/ontology/MESH/Q000175 http://purl.bioontology.org/ontology/MESH/Q000628 http://purl.bioontology.org/ontology/MESH/Q000648 http://purl.bioontology.org/ontology/MESH/Q000276 http://purl.bioontology.org/ontology/MESH/Q000134 http://purl.bioontology.org/ontology/MESH/Q000139 http://purl.bioontology.org/ontology/MESH/Q000266 http://purl.bioontology.org/ontology/MESH/Q000378 http://purl.bioontology.org/ontology/MESH/Q000517 http://purl.bioontology.org/ontology/MESH/Q000662 http://purl.bioontology.org/ontology/MESH/Q000469 http://purl.bioontology.org/ontology/MESH/Q000151 http://purl.bioontology.org/ontology/MESH/Q000150 http://purl.bioontology.org/ontology/MESH/Q000821 http://purl.bioontology.org/ontology/MESH/Q000191 http://purl.bioontology.org/ontology/MESH/Q000196 http://purl.bioontology.org/ontology/MESH/Q000473 http://purl.bioontology.org/ontology/MESH/Q000145 http://purl.bioontology.org/ontology/MESH/Q000737 http://purl.bioontology.org/ontology/MESH/Q000382 http://purl.bioontology.org/ontology/MESH/Q000451 http://purl.bioontology.org/ontology/MESH/Q000453 http://purl.bioontology.org/ontology/MESH/Q000534 http://purl.bioontology.org/ontology/MESH/Q000532 http://purl.bioontology.org/ontology/MESH/Q000503 http://purl.bioontology.org/ontology/MESH/Q000188 http://purl.bioontology.org/ontology/MESH/Q000235 http://purl.bioontology.org/ontology/MESH/Q000201 http://purl.bioontology.org/ontology/MESH/Q000209 http://purl.bioontology.org/ontology/MESH/Q000208 http://purl.bioontology.org/ontology/MESH/Q000601 http://purl.bioontology.org/ontology/MESH/Q000000981 http://purl.bioontology.org/ontology/MESH/Q000556 http://purl.bioontology.org/ontology/MESH/Q000652 |
|
| Inverse of RO | ||
| Mapped from | ||
| MDA |
19990101 |
|
| MMR |
20180615 |
|
| MN |
C04.557.580.625.600.725 C04.557.465.625.600.725 C11.270.862 C11.319.475.760 C04.588.364.818.760 C04.557.470.670.725 C11.768.717.760 |
|
| notation |
D012175 |
|
| prefLabel |
Retinoblastoma |
|
| TERMUI |
T371983 T727501 T036238 T371984 T036235 T036237 T036236 T371985 |
|
| TH |
NLM (2000) NLM (1966) GHR (2014) NLM (1998) NLM (2011) ORD (2010) |
|
| tui |
T191 |
|
| subClassOf |
http://purl.bioontology.org/ontology/MESH/D019572 |