loading...| Preferred Name |
Supranuclear Palsy, Progressive |
|
| Synonyms |
Supranuclear Ophthalmoplegia, Progressive |
|
| Definitions |
A degenerative disease of the central nervous system characterized by balance difficulties; OCULAR MOTILITY DISORDERS (supranuclear ophthalmoplegia); DYSARTHRIA; swallowing difficulties; and axial DYSTONIA. Onset is usually in the fifth decade and disease progression occurs over several years. Pathologic findings include neurofibrillary degeneration and neuronal loss in the dorsal MESENCEPHALON; SUBTHALAMIC NUCLEUS; RED NUCLEUS; pallidum; dentate nucleus; and vestibular nuclei. (From Adams et al., Principles of Neurology, 6th ed, pp1076-7) |
|
| ID |
http://purl.bioontology.org/ontology/MESH/D013494 |
|
| altLabel |
Supranuclear Ophthalmoplegia, Progressive Steele Richardson Olszewski Disease Progressive Supranuclear Palsy Steele-Richardson-Olszewski Disease Richardson's Syndrome Progressive Supranuclear Ophthalmoplegia Steele-Richardson-Olszewski Syndrome Richardson Syndrome Palsy, Progressive Supranuclear Steele Richardson Olszewski Syndrome Progressive Supranuclear Palsies Supranuclear Palsy, Progressive, 1 Progressive Supranuclear Palsy 1 Supranuclear Palsies, Progressive Ophthalmoplegia, Progressive Supranuclear |
|
| AQL |
BL CF CI CL CN CO DG DH DI DT EC EH EM EN EP ET GE HI IM ME MI MO NU PA PC PP PS PX RH RT SU TH UR VE VI |
|
| cui |
C0038868 C4551863 C4551862 |
|
| DC |
1 |
|
| definition |
A degenerative disease of the central nervous system characterized by balance difficulties; OCULAR MOTILITY DISORDERS (supranuclear ophthalmoplegia); DYSARTHRIA; swallowing difficulties; and axial DYSTONIA. Onset is usually in the fifth decade and disease progression occurs over several years. Pathologic findings include neurofibrillary degeneration and neuronal loss in the dorsal MESENCEPHALON; SUBTHALAMIC NUCLEUS; RED NUCLEUS; pallidum; dentate nucleus; and vestibular nuclei. (From Adams et al., Principles of Neurology, 6th ed, pp1076-7) |
|
| DX |
19870101 |
|
| HN |
1987 |
|
| Inverse of AQ |
http://purl.bioontology.org/ontology/MESH/Q000097 http://purl.bioontology.org/ontology/MESH/Q000178 http://purl.bioontology.org/ontology/MESH/Q000175 http://purl.bioontology.org/ontology/MESH/Q000628 http://purl.bioontology.org/ontology/MESH/Q000276 http://purl.bioontology.org/ontology/MESH/Q000134 http://purl.bioontology.org/ontology/MESH/Q000139 http://purl.bioontology.org/ontology/MESH/Q000266 http://purl.bioontology.org/ontology/MESH/Q000378 http://purl.bioontology.org/ontology/MESH/Q000517 http://purl.bioontology.org/ontology/MESH/Q000662 http://purl.bioontology.org/ontology/MESH/Q000469 http://purl.bioontology.org/ontology/MESH/Q000151 http://purl.bioontology.org/ontology/MESH/Q000150 http://purl.bioontology.org/ontology/MESH/Q000821 http://purl.bioontology.org/ontology/MESH/Q000191 http://purl.bioontology.org/ontology/MESH/Q000196 http://purl.bioontology.org/ontology/MESH/Q000473 http://purl.bioontology.org/ontology/MESH/Q000145 http://purl.bioontology.org/ontology/MESH/Q000382 http://purl.bioontology.org/ontology/MESH/Q000451 http://purl.bioontology.org/ontology/MESH/Q000453 http://purl.bioontology.org/ontology/MESH/Q000534 http://purl.bioontology.org/ontology/MESH/Q000532 http://purl.bioontology.org/ontology/MESH/Q000503 http://purl.bioontology.org/ontology/MESH/Q000188 http://purl.bioontology.org/ontology/MESH/Q000235 http://purl.bioontology.org/ontology/MESH/Q000201 http://purl.bioontology.org/ontology/MESH/Q000209 http://purl.bioontology.org/ontology/MESH/Q000208 http://purl.bioontology.org/ontology/MESH/Q000601 http://purl.bioontology.org/ontology/MESH/Q000000981 http://purl.bioontology.org/ontology/MESH/Q000652 |
|
| Machine permutation |
1987 |
|
| Mapped from |
http://purl.bioontology.org/ontology/MESH/C567050 http://purl.bioontology.org/ontology/MESH/C563717 http://purl.bioontology.org/ontology/MESH/C537240 |
|
| MDA |
19860401 |
|
| MMR |
20200206 |
|
| MN |
C10.228.140.079.882 C10.597.622.447.690 C10.292.562.750.500 C10.574.945.500 C23.888.592.636.447.690 C11.590.472.500 C10.228.662.700 |
|
| notation |
D013494 |
|
| prefLabel |
Supranuclear Palsy, Progressive |
|
| TERMUI |
T842339 T364585 T364586 T364587 T039601 T039599 T842340 T039600 T811912 T000994042 |
|
| TH |
OMIM (2013) NLM (2000) NLM (1987) UNK (19XX) NLM (2021) GHR (2014) ORD (2010) |
|
| tui |
T047 |
|
| subClassOf |
http://purl.bioontology.org/ontology/MESH/D009069 http://purl.bioontology.org/ontology/MESH/D009886 |