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Medical Subject Headings
Id | http://purl.bioontology.org/ontology/MESH/D015854
http://purl.bioontology.org/ontology/MESH/D015854
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Preferred Name | Up-Regulation |
Definitions |
A positive regulatory effect on physiological processes at the molecular, cellular, or systemic level. At the molecular level, the major regulatory sites include membrane receptors, genes (GENE EXPRESSION REGULATION), mRNAs (RNA, MESSENGER), and proteins.
A positive regulatory process that increases ligand-receptor interactions. Increase in receptor binding after ligand exposure can result from receptor activation, aggregation, increase in half-life, and/or an increase in gene expression that leads to de novo receptor synthesis.
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Synonyms |
Upregulation
Up-Regulation (Physiology)
Receptor Up-Regulation
Up Regulation
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Type | http://www.w3.org/2002/07/owl#Class |
All Properties
definition | A positive regulatory effect on physiological processes at the molecular, cellular, or systemic level. At the molecular level, the major regulatory sites include membrane receptors, genes (GENE EXPRESSION REGULATION), mRNAs (RNA, MESSENGER), and proteins. A positive regulatory process that increases ligand-receptor interactions. Increase in receptor binding after ligand exposure can result from receptor activation, aggregation, increase in half-life, and/or an increase in gene expression that leads to de novo receptor synthesis. |
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altLabel |
Upregulation
Up-Regulation (Physiology)
Receptor Up-Regulation
Up Regulation
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prefLabel | Up-Regulation
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TH |
NLM (2002)
NLM (1990)
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notation | D015854
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DX | 19900101
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Machine permutation | 2002; see Up-Regulation (Physiology) 1990-2001
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MN |
G07.690.773.998
G05.308.850
G02.111.905
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FX |
D015536
D025461
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MMR | 20160617
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AQL | DE ES GE IM PH RE
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HN | 2002 (1990)
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subClassOf | |
Semantic type UMLS property | |
DC | 1
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MDA | 19890526
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Inverse of RO | |
type | |
tui | T044
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cui |
C0041904
C0949479
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Inverse of AQ |
See more
See less
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TERMUI |
T047048
T430673
T047049
T047050
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Notes
Subject | Author | Type | Class | Created |
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Missing Publication Format | kglibrarian | Comment | 2022-11-01 | |
The RDF format of MeSH is inaccessible | AAmina | Comment | 2015-03-08 |
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