loading...| Preferred Name |
Mutagenesis, Insertional |
|
| Synonyms |
Insertional Mutagenesis |
|
| Definitions |
Mutagenesis where the mutation is caused by the introduction of foreign DNA sequences into a gene or extragenic sequence. This may occur spontaneously in vivo or be experimentally induced in vivo or in vitro. Proviral DNA insertions into or adjacent to a cellular proto-oncogene can interrupt GENETIC TRANSLATION of the coding sequences or interfere with recognition of regulatory elements and cause unregulated expression of the proto-oncogene resulting in tumor formation. |
|
| ID |
http://purl.bioontology.org/ontology/MESH/D016254 |
|
| altLabel |
Insertional Mutagenesis Linker-Insertion Mutagenesis Insertion Mutations Insertional Activations Insertion, Gene Linker Insertion Mutagenesis Sequence Insertions Insertional Mutagenesis, Viral Gene Insertion Insertional Activation Insertion, Sequence Mutagenesis, Cassette Gene Insertions Mutagenesis, Viral Insertional Insertions, Gene Insertions, Sequence Activation, Insertional Mutagenesis, Linker-Insertion Mutations, Insertion Activations, Insertional Cassette Mutagenesis Sequence Insertion Viral Insertional Mutagenesis Insertion Mutation Mutation, Insertion |
|
| AQL |
DE EC GE HI IM IS MT PH RE SN ST |
|
| cui |
C0079627 C0080314 C1955830 C1955829 C0079704 C0079868 C0079867 C1512796 |
|
| DC |
1 |
|
| definition |
Mutagenesis where the mutation is caused by the introduction of foreign DNA sequences into a gene or extragenic sequence. This may occur spontaneously in vivo or be experimentally induced in vivo or in vitro. Proviral DNA insertions into or adjacent to a cellular proto-oncogene can interrupt GENETIC TRANSLATION of the coding sequences or interfere with recognition of regulatory elements and cause unregulated expression of the proto-oncogene resulting in tumor formation. |
|
| DX |
19910101 |
|
| FX |
D004251 |
|
| HN |
91 |
|
| Inverse of AQ |
http://purl.bioontology.org/ontology/MESH/Q000276 http://purl.bioontology.org/ontology/MESH/Q000266 http://purl.bioontology.org/ontology/MESH/Q000379 http://purl.bioontology.org/ontology/MESH/Q000706 http://purl.bioontology.org/ontology/MESH/Q000191 http://purl.bioontology.org/ontology/MESH/Q000592 http://purl.bioontology.org/ontology/MESH/Q000295 http://purl.bioontology.org/ontology/MESH/Q000502 http://purl.bioontology.org/ontology/MESH/Q000187 |
|
| Inverse of RO |
http://purl.bioontology.org/ontology/MESH/D020087 http://purl.bioontology.org/ontology/MESH/D018626 http://purl.bioontology.org/ontology/MESH/D020071 |
|
| Machine permutation |
91 |
|
| MDA |
19900529 |
|
| MMR |
20180629 |
|
| MN |
G05.365.590.575 G05.558.550 E05.393.420.601.550 |
|
| notation |
D016254 |
|
| prefLabel |
Mutagenesis, Insertional |
|
| TERMUI |
T048402 T692080 T692081 T048398 T048397 T692082 T048400 T048399 T048401 |
|
| TH |
NLM (1991) NLM (2008) |
|
| tui |
T049 T063 T045 |
|
| subClassOf |
http://purl.bioontology.org/ontology/MESH/D015202 |