Medical Subject Headings

Last uploaded: January 16, 2025
Id http://purl.bioontology.org/ontology/MESH/D016335
http://purl.bioontology.org/ontology/MESH/D016335
Preferred Name

Zinc Fingers

Definitions
Motifs in DNA- and RNA-binding proteins whose amino acids are folded into a single structural unit around a zinc atom. In the classic zinc finger, one zinc atom is bound to two cysteines and two histidines. In between the cysteines and histidines are 12 residues which form a DNA binding fingertip. By variations in the composition of the sequences in the fingertip and the number and spacing of tandem repeats of the motif, zinc fingers can form a large number of different sequence specific binding sites.
Synonyms
Finger, Zinc
Zinc Finger DNA-Binding Domains
Motif, Zinc Finger
Motifs, Zinc Finger
Zinc Finger DNA Binding Domains
Fingers, Zinc
Zinc Finger Motif
Zinc Finger Motifs
Zinc Finger
Type http://www.w3.org/2002/07/owl#Class
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