loading...| Preferred Name |
Frameshift Mutation |
|
| Synonyms |
Insertion, Out-of-Frame |
|
| Definitions |
A type of mutation in which a number of NUCLEOTIDES deleted from or inserted into a protein coding sequence is not divisible by three, thereby causing an alteration in the READING FRAMES of the entire coding sequence downstream of the mutation. These mutations may be induced by certain types of MUTAGENS or may occur spontaneously. |
|
| ID |
http://purl.bioontology.org/ontology/MESH/D016368 |
|
| altLabel |
Insertion, Out-of-Frame Out-of-Frame Insertions Out-of-Frame Insertion Out-of-Frame Mutations Mutation, Frame Shift Mutations, Frame Shift Mutations, Frameshift Out-of-Frame Mutation Mutations, Out-of-Frame Frame Shift Mutation Frame Shift Mutations Deletions, Out-of-Frame Out of Frame Deletion Mutation, Frameshift Insertions, Out-of-Frame Out-of-Frame Deletion Deletion, Out-of-Frame Frameshift Mutations Out of Frame Insertion Out of Frame Mutation Out-of-Frame Deletions Mutation, Out-of-Frame |
|
| AN |
do not confuse with FRAMESHIFTING, RIBOSOMAL, physiology process & form of genetic translation; do not confuse effects of drug & radiation on frameshift mutation with drug- & radiation-induced frameshift mutation |
|
| AQL |
DE GE IM PH RE |
|
| cui |
C1955831 C0079380 C1563708 |
|
| DC |
1 |
|
| definition |
A type of mutation in which a number of NUCLEOTIDES deleted from or inserted into a protein coding sequence is not divisible by three, thereby causing an alteration in the READING FRAMES of the entire coding sequence downstream of the mutation. These mutations may be induced by certain types of MUTAGENS or may occur spontaneously. |
|
| DX |
19910101 |
|
| HN |
91 |
|
| Inverse of AQ |
http://purl.bioontology.org/ontology/MESH/Q000276 http://purl.bioontology.org/ontology/MESH/Q000502 http://purl.bioontology.org/ontology/MESH/Q000187 |
|
| Inverse of RO | ||
| Machine permutation |
91 |
|
| MDA |
19900525 |
|
| MMR |
20080708 |
|
| MN |
G05.365.590.265 |
|
| notation |
D016368 |
|
| prefLabel |
Frameshift Mutation |
|
| TERMUI |
T048911 T048910 T606242 T048909 T606243 T691502 |
|
| TH |
NLM (1993) NLM (1991) NLM (2008) NLM (2006) |
|
| tui |
T049 T045 |
|
| subClassOf |