Link to this page
Medical Subject Headings
Last uploaded:
January 16, 2025
Jump to:
| Id | http://purl.bioontology.org/ontology/MESH/D016559
http://purl.bioontology.org/ontology/MESH/D016559
|
|---|---|
| Preferred Name | Tacrolimus |
| Definitions |
A macrolide isolated from the culture broth of a strain of Streptomyces tsukubaensis that has strong immunosuppressive activity in vivo and prevents the activation of T-lymphocytes in response to antigenic or mitogenic stimulation in vitro.
|
| Synonyms |
Tacrolimus Anhydrous
Anhydrous, Tacrolimus
FK506
FR-900506
Anhydrous Tacrolimus
15,19-Epoxy-3H-pyrido(2,1-c)(1,4)oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone, 5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-5,19-dihydroxy-3-(2-(4-hydroxy-3-methoxycyclohexyl)-1-methylethenyl)-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propenyl)-, monohydrate, (3S-(3R*(E(1S*,3S*,4S*)),4S*,5R*,8S*,9E,12R*,14R*,15S*,16R*,18S*,19S*,26aR*))-
Tacrolimus, Anhydrous
FK-506
FR 900506
Prograf
FK 506
Prograft
FR900506
See more
See less
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A macrolide isolated from the culture broth of a strain of Streptomyces tsukubaensis that has strong immunosuppressive activity in vivo and prevents the activation of T-lymphocytes in response to antigenic or mitogenic stimulation in vitro. |
|---|---|
| altLabel | Tacrolimus Anhydrous
Anhydrous, Tacrolimus
FK506
FR-900506
Anhydrous Tacrolimus
15,19-Epoxy-3H-pyrido(2,1-c)(1,4)oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone, 5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-5,19-dihydroxy-3-(2-(4-hydroxy-3-methoxycyclohexyl)-1-methylethenyl)-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propenyl)-, monohydrate, (3S-(3R*(E(1S*,3S*,4S*)),4S*,5R*,8S*,9E,12R*,14R*,15S*,16R*,18S*,19S*,26aR*))-
Tacrolimus, Anhydrous
FK-506
FR 900506
Prograf
FK 506
Prograft
FR900506
See more
See less
|
| prefLabel | Tacrolimus
|
| TH |
NLM (1996)
US
MX
NL
NLM (1999)
CA
FDA SRS (2014)
USAN (1992)
ES
NLM (1992)
INN (19XX)
NLM (2013)
DE
AU
NLM (2014)
FR
IE
See more
See less
|
| notation | D016559
|
| RR |
109581-93-3 (Tacrolimus)
Y5L2157C4J
|
| DX | 19920101
|
| Machine permutation | 96; was FK-506 1992-95; FK-506 was indexed under ANTIBIOTICS, MACROLIDE 1989-91 & PYRIDINES 1987-89
|
| MN | D02.540.505.810
|
| PA |
D065095
D007166
|
| MMR | 20160701
|
| Mapped from |
See more
See less
|
| AQL | AA AD AE AG AI AN BL CF CH CL CS EC HI IM IP ME PD PK PO RE SD ST TO TU UR
|
| HN | 96; was FK-506 1992-95, was FK 506 (NM) 1987-91
|
| subClassOf | |
| Semantic type UMLS property | |
| Inverse of RB |
WM0HAQ4WNM
Y5L2157C4J
0
|
| LT | TRD
|
| DC | 1
|
| MDA | 19910424
|
| type | |
| tui |
T109
T121
|
| cui |
C0678125
C0771204
C0729219
C0729218
C0085149
|
| isa | |
| Inverse of AQ |
See more
See less
|
| OL | use TACROLIMUS (NM) to search FK-506 1987-91
|
| TERMUI |
T049537
T049539
T619253
T822955
T049536
T049538
T359657
T049540
See more
See less
|
Add comment
| Delete | Subject | Author | Type | Created |
|---|---|---|---|---|
| No notes to display |