Medical Subject Headings

Last uploaded: January 16, 2025

Id	http://purl.bioontology.org/ontology/MESH/D016875 http://purl.bioontology.org/ontology/MESH/D016875
Preferred Name	tau Proteins
Definitions	Microtubule-associated proteins that are mainly expressed in neurons. Tau proteins constitute several isoforms and play an important role in the assembly of tubulin monomers into microtubules and in maintaining the cytoskeleton and axonal transport. Aggregation of specific sets of tau proteins in filamentous inclusions is the common feature of intraneuronal and glial fibrillar lesions (NEUROFIBRILLARY TANGLES; NEUROPIL THREADS) in numerous neurodegenerative disorders (ALZHEIMER DISEASE; TAUOPATHIES).
Synonyms	tau Protein Protein, tau Proteins, tau
Type	http://www.w3.org/2002/07/owl#Class

definition	Microtubule-associated proteins that are mainly expressed in neurons. Tau proteins constitute several isoforms and play an important role in the assembly of tubulin monomers into microtubules and in maintaining the cytoskeleton and axonal transport. Aggregation of specific sets of tau proteins in filamentous inclusions is the common feature of intraneuronal and glial fibrillar lesions (NEUROFIBRILLARY TANGLES; NEUROPIL THREADS) in numerous neurodegenerative disorders (ALZHEIMER DISEASE; TAUOPATHIES).
altLabel	tau Protein Protein, tau Proteins, tau
prefLabel	tau Proteins
TH	NLM (1992)
notation	D016875
DX	19920101
Machine permutation	1992; TAU (NM) was indexed under MICROTUBULE-ASSOCIATED PROTEINS 1985-91 & under PROTEINS 1977-84
MN	D12.776.631.560.510 D12.776.220.600.450.510
FX	D024801
MMR	20160705
Mapped from	http://purl.bioontology.org/ontology/MESH/C000599422 http://purl.bioontology.org/ontology/MESH/C000710267 http://purl.bioontology.org/ontology/MESH/C000630947 http://purl.bioontology.org/ontology/MESH/C558298 http://purl.bioontology.org/ontology/MESH/C093267 http://purl.bioontology.org/ontology/MESH/C000598882 http://purl.bioontology.org/ontology/MESH/C077510 http://purl.bioontology.org/ontology/MESH/C430266 http://purl.bioontology.org/ontology/MESH/C489131 http://purl.bioontology.org/ontology/MESH/C458340 http://purl.bioontology.org/ontology/MESH/C054369 See more See less
AQL	AD AE AG AI AN BI BL CF CH CL CS DE DF EC GE HI IM IP ME PD PH PK PO RE SD ST TO TU UL UR
HN	1992; use TAU (NM) 1977-91
subClassOf	http://purl.bioontology.org/ontology/MESH/D008869
Semantic type UMLS property	http://purl.bioontology.org/ontology/STY/T123 http://purl.bioontology.org/ontology/STY/T116
Inverse of RB	0
DC	1
MDA	19910712
Inverse of RO	http://purl.bioontology.org/ontology/MESH/D024801 http://purl.bioontology.org/ontology/MESH/D000544
type	http://www.w3.org/2002/07/owl#Class
tui	T116 T123
cui	C0085401
Inverse of AQ	http://purl.bioontology.org/ontology/MESH/Q000097 http://purl.bioontology.org/ontology/MESH/Q000096 http://purl.bioontology.org/ontology/MESH/Q000172 http://purl.bioontology.org/ontology/MESH/Q000627 http://purl.bioontology.org/ontology/MESH/Q000648 http://purl.bioontology.org/ontology/MESH/Q000493 http://purl.bioontology.org/ontology/MESH/Q000494 http://purl.bioontology.org/ontology/MESH/Q000276 http://purl.bioontology.org/ontology/MESH/Q000138 http://purl.bioontology.org/ontology/MESH/Q000134 http://purl.bioontology.org/ontology/MESH/Q000266 http://purl.bioontology.org/ontology/MESH/Q000378 http://purl.bioontology.org/ontology/MESH/Q000008 http://purl.bioontology.org/ontology/MESH/Q000009 http://purl.bioontology.org/ontology/MESH/Q000032 http://purl.bioontology.org/ontology/MESH/Q000037 http://purl.bioontology.org/ontology/MESH/Q000191 http://purl.bioontology.org/ontology/MESH/Q000302 http://purl.bioontology.org/ontology/MESH/Q000145 http://purl.bioontology.org/ontology/MESH/Q000592 http://purl.bioontology.org/ontology/MESH/Q000737 http://purl.bioontology.org/ontology/MESH/Q000819 http://purl.bioontology.org/ontology/MESH/Q000502 http://purl.bioontology.org/ontology/MESH/Q000506 http://purl.bioontology.org/ontology/MESH/Q000187 http://purl.bioontology.org/ontology/MESH/Q000235 http://purl.bioontology.org/ontology/MESH/Q000633 http://purl.bioontology.org/ontology/MESH/Q000600 http://purl.bioontology.org/ontology/MESH/Q000652 http://purl.bioontology.org/ontology/MESH/Q000528 See more See less
OL	use TAU PROTEINS (NM) to search TAU (NM) 1980-90
TERMUI	T050514 T050515

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