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Medical Subject Headings

Last uploaded: January 16, 2025
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Id http://purl.bioontology.org/ontology/MESH/D016898
http://purl.bioontology.org/ontology/MESH/D016898
Preferred Name

Interferon-alpha
Definitions
One of the type I interferons produced by peripheral blood leukocytes or lymphoblastoid cells. In addition to antiviral activity, it activates NATURAL KILLER CELLS and B-LYMPHOCYTES, and down-regulates VASCULAR ENDOTHELIAL GROWTH FACTOR expression through PI-3 KINASE and MAPK KINASES signaling pathways.
Synonyms
Interferon alpha-J
Leukocyte Interferon
Lymphoblastoid Interferon
Interferon alpha 1
Interferon alpha-1
Interferon alpha J
Interferon alpha-T
IFN alpha D
LeIF I
alpha Interferon
Interferon Alfa
Leif D
Interferon alpha5
Lymphoblast Interferon
Interferon, Lymphoblast
Interferon alpha-4
IFN alpha5
Interferon alpha 17
Interferon, alpha
Interferon alpha 4
Interferon alpha 5
Interferon, Lymphoblastoid
Interferon, Leukocyte
LeIF J
Interferon alpha4
Interferon alpha-7
Interferon alpha-88
Interferon alpha 7
Interferon alpha T
alpha-Interferon
Interferon alpha 88
IFN-alpha5
Interferon alpha-17
Interferon alpha
IFN-alpha D
Interferon alpha-5
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Type http://www.w3.org/2002/07/owl#Class

All Properties

definition

One of the type I interferons produced by peripheral blood leukocytes or lymphoblastoid cells. In addition to antiviral activity, it activates NATURAL KILLER CELLS and B-LYMPHOCYTES, and down-regulates VASCULAR ENDOTHELIAL GROWTH FACTOR expression through PI-3 KINASE and MAPK KINASES signaling pathways.
altLabel
Interferon alpha-J
Leukocyte Interferon
Lymphoblastoid Interferon
Interferon alpha 1
Interferon alpha-1
Interferon alpha J
Interferon alpha-T
IFN alpha D
LeIF I
alpha Interferon
Interferon Alfa
Leif D
Interferon alpha5
Lymphoblast Interferon
Interferon, Lymphoblast
Interferon alpha-4
IFN alpha5
Interferon alpha 17
Interferon, alpha
Interferon alpha 4
Interferon alpha 5
Interferon, Lymphoblastoid
Interferon, Leukocyte
LeIF J
Interferon alpha4
Interferon alpha-7
Interferon alpha-88
Interferon alpha 7
Interferon alpha T
alpha-Interferon
Interferon alpha 88
IFN-alpha5
Interferon alpha-17
Interferon alpha
IFN-alpha D
Interferon alpha-5
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prefLabel
Interferon-alpha
TH
NLM (2012)
NLM (1992)
notation
D016898
DX
19920101
Machine permutation
1992; see INTERFERON TYPE I 1983-1991, INTERFERON ALPHA-1 was indexed under INTERFERON-ALPHA 2001-2011, INTERFERON-ALPHA 2 was indexed under INTERFERON-ALPHA 1997-2011, INTERFERON ALPHA4 was indexed under INTERFERON-ALPHA 1993-2001, INTERFERON ALPHA5 was indexed under INTERFERON-ALPHA 1996-2001
MN
D23.529.374.440.890.250
D12.644.276.374.440.890.250
D12.776.467.374.440.890.250
PA
D000998
D007155
MMR
20180111
Mapped from
http://purl.bioontology.org/ontology/MESH/C554162
http://purl.bioontology.org/ontology/MESH/C554163
http://purl.bioontology.org/ontology/MESH/C554160
http://purl.bioontology.org/ontology/MESH/C554164
http://purl.bioontology.org/ontology/MESH/C000621575
http://purl.bioontology.org/ontology/MESH/C000724048
http://purl.bioontology.org/ontology/MESH/C047910
http://purl.bioontology.org/ontology/MESH/C554783
http://purl.bioontology.org/ontology/MESH/C471357
http://purl.bioontology.org/ontology/MESH/C504514
http://purl.bioontology.org/ontology/MESH/C504513
http://purl.bioontology.org/ontology/MESH/C118689
http://purl.bioontology.org/ontology/MESH/C076799
http://purl.bioontology.org/ontology/MESH/C090879
http://purl.bioontology.org/ontology/MESH/C531108
http://purl.bioontology.org/ontology/MESH/C554129
http://purl.bioontology.org/ontology/MESH/C554126
http://purl.bioontology.org/ontology/MESH/C000711828
http://purl.bioontology.org/ontology/MESH/C412623
http://purl.bioontology.org/ontology/MESH/C050739
http://purl.bioontology.org/ontology/MESH/C452189
http://purl.bioontology.org/ontology/MESH/C080665
http://purl.bioontology.org/ontology/MESH/C554150
http://purl.bioontology.org/ontology/MESH/C554156
http://purl.bioontology.org/ontology/MESH/C554158
http://purl.bioontology.org/ontology/MESH/C554159
http://purl.bioontology.org/ontology/MESH/C120240
http://purl.bioontology.org/ontology/MESH/C100416
http://purl.bioontology.org/ontology/MESH/C068567
http://purl.bioontology.org/ontology/MESH/C114167
http://purl.bioontology.org/ontology/MESH/C085827
http://purl.bioontology.org/ontology/MESH/C473631
http://purl.bioontology.org/ontology/MESH/C120238
http://purl.bioontology.org/ontology/MESH/C120239
http://purl.bioontology.org/ontology/MESH/C554329
http://purl.bioontology.org/ontology/MESH/C554326
http://purl.bioontology.org/ontology/MESH/C554324
http://purl.bioontology.org/ontology/MESH/C554325
http://purl.bioontology.org/ontology/MESH/C554327
http://purl.bioontology.org/ontology/MESH/C438724
http://purl.bioontology.org/ontology/MESH/C417083
http://purl.bioontology.org/ontology/MESH/C058673
http://purl.bioontology.org/ontology/MESH/C554330
http://purl.bioontology.org/ontology/MESH/C554334
http://purl.bioontology.org/ontology/MESH/C554331
http://purl.bioontology.org/ontology/MESH/C554333
http://purl.bioontology.org/ontology/MESH/C554332
http://purl.bioontology.org/ontology/MESH/C472347
http://purl.bioontology.org/ontology/MESH/C472348
http://purl.bioontology.org/ontology/MESH/C044342
http://purl.bioontology.org/ontology/MESH/C501864
http://purl.bioontology.org/ontology/MESH/C571406
http://purl.bioontology.org/ontology/MESH/C577353
http://purl.bioontology.org/ontology/MESH/C543152
http://purl.bioontology.org/ontology/MESH/C521991
http://purl.bioontology.org/ontology/MESH/C056556
http://purl.bioontology.org/ontology/MESH/C111627
http://purl.bioontology.org/ontology/MESH/C040774
http://purl.bioontology.org/ontology/MESH/C040773
http://purl.bioontology.org/ontology/MESH/C113934
http://purl.bioontology.org/ontology/MESH/C519328
http://purl.bioontology.org/ontology/MESH/C469326
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AQL
AD AE AG AI AN BI BL CF CH CL CS DE DF EC GE HI IM IP ME PD PH PK PO RE SD ST TO TU UL UR
HN
1992; for INTERFERON, LYMPHOBLAST and INTERFERON, LEUKOCYTE use INTERFERON TYPE I 1989-1991
subClassOf
Semantic type UMLS property
Inverse of RB
0
DC
1
MDA
19910530
type
tui
T116
T129
T121
cui
C1098214
C3887953
C3887954
C0002199
C0391393
C0219697
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isa
Inverse of AQ
http://purl.bioontology.org/ontology/MESH/Q000097
http://purl.bioontology.org/ontology/MESH/Q000096
http://purl.bioontology.org/ontology/MESH/Q000172
http://purl.bioontology.org/ontology/MESH/Q000627
http://purl.bioontology.org/ontology/MESH/Q000648
http://purl.bioontology.org/ontology/MESH/Q000493
http://purl.bioontology.org/ontology/MESH/Q000494
http://purl.bioontology.org/ontology/MESH/Q000276
http://purl.bioontology.org/ontology/MESH/Q000138
http://purl.bioontology.org/ontology/MESH/Q000134
http://purl.bioontology.org/ontology/MESH/Q000266
http://purl.bioontology.org/ontology/MESH/Q000378
http://purl.bioontology.org/ontology/MESH/Q000008
http://purl.bioontology.org/ontology/MESH/Q000009
http://purl.bioontology.org/ontology/MESH/Q000032
http://purl.bioontology.org/ontology/MESH/Q000037
http://purl.bioontology.org/ontology/MESH/Q000191
http://purl.bioontology.org/ontology/MESH/Q000302
http://purl.bioontology.org/ontology/MESH/Q000145
http://purl.bioontology.org/ontology/MESH/Q000592
http://purl.bioontology.org/ontology/MESH/Q000737
http://purl.bioontology.org/ontology/MESH/Q000819
http://purl.bioontology.org/ontology/MESH/Q000502
http://purl.bioontology.org/ontology/MESH/Q000506
http://purl.bioontology.org/ontology/MESH/Q000187
http://purl.bioontology.org/ontology/MESH/Q000235
http://purl.bioontology.org/ontology/MESH/Q000633
http://purl.bioontology.org/ontology/MESH/Q000600
http://purl.bioontology.org/ontology/MESH/Q000652
http://purl.bioontology.org/ontology/MESH/Q000528
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TERMUI
T782163
T782161
T050583
T050581
T050582
T782160
T782166
T782202
T782165
T050584
T050587
T782164
T784696
T294083
T467477
T782201
T782199
T050585
T050590
T782200
T782198
T782162
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