loading...| Preferred Name |
Aphasia, Primary Progressive |
|
| Synonyms |
Progressive Aphasias, Primary Aphasias, Primary Progressive |
|
| Definitions |
A progressive form of dementia characterized by the global loss of language abilities and initial preservation of other cognitive functions. Fluent and nonfluent subtypes have been described. Eventually a pattern of global cognitive dysfunction, similar to ALZHEIMER DISEASE, emerges. Pathologically, there are no Alzheimer or PICK DISEASE like changes, however, spongiform changes of cortical layers II and III are present in the TEMPORAL LOBE and FRONTAL LOBE. (From Brain 1998 Jan;121(Pt 1):115-26) |
|
| ID |
http://purl.bioontology.org/ontology/MESH/D018888 |
|
| altLabel |
Progressive Aphasias, Primary Syndrome, Mesulam Primary Progressive Aphasias Syndrome, Mesulam's Mesulam's Syndrome Primary Progressive Aphasia Progressive Aphasia, Primary Mesulam Syndrome Aphasias, Primary Progressive |
|
| AN |
a clinical entity: do not confuse with descriptions of the progression of aphasia in case reports |
|
| AQL |
BL CF CI CL CO DG DH DI DT EC EH EN EP ET GE HI IM ME MI MO NU PA PC PP PS PX RH SU TH UR VI |
|
| cui |
C0282513 |
|
| DC |
1 |
|
| definition |
A progressive form of dementia characterized by the global loss of language abilities and initial preservation of other cognitive functions. Fluent and nonfluent subtypes have been described. Eventually a pattern of global cognitive dysfunction, similar to ALZHEIMER DISEASE, emerges. Pathologically, there are no Alzheimer or PICK DISEASE like changes, however, spongiform changes of cortical layers II and III are present in the TEMPORAL LOBE and FRONTAL LOBE. (From Brain 1998 Jan;121(Pt 1):115-26) |
|
| DX |
19960101 |
|
| HN |
1996 |
|
| Inverse of AQ |
http://purl.bioontology.org/ontology/MESH/Q000097 http://purl.bioontology.org/ontology/MESH/Q000178 http://purl.bioontology.org/ontology/MESH/Q000175 http://purl.bioontology.org/ontology/MESH/Q000628 http://purl.bioontology.org/ontology/MESH/Q000276 http://purl.bioontology.org/ontology/MESH/Q000134 http://purl.bioontology.org/ontology/MESH/Q000139 http://purl.bioontology.org/ontology/MESH/Q000266 http://purl.bioontology.org/ontology/MESH/Q000378 http://purl.bioontology.org/ontology/MESH/Q000517 http://purl.bioontology.org/ontology/MESH/Q000469 http://purl.bioontology.org/ontology/MESH/Q000150 http://purl.bioontology.org/ontology/MESH/Q000821 http://purl.bioontology.org/ontology/MESH/Q000191 http://purl.bioontology.org/ontology/MESH/Q000473 http://purl.bioontology.org/ontology/MESH/Q000145 http://purl.bioontology.org/ontology/MESH/Q000382 http://purl.bioontology.org/ontology/MESH/Q000451 http://purl.bioontology.org/ontology/MESH/Q000453 http://purl.bioontology.org/ontology/MESH/Q000534 http://purl.bioontology.org/ontology/MESH/Q000503 http://purl.bioontology.org/ontology/MESH/Q000188 http://purl.bioontology.org/ontology/MESH/Q000235 http://purl.bioontology.org/ontology/MESH/Q000201 http://purl.bioontology.org/ontology/MESH/Q000209 http://purl.bioontology.org/ontology/MESH/Q000208 http://purl.bioontology.org/ontology/MESH/Q000601 http://purl.bioontology.org/ontology/MESH/Q000000981 http://purl.bioontology.org/ontology/MESH/Q000652 |
|
| Inverse of RO | ||
| Machine permutation |
1996 |
|
| MDA |
19941227 |
|
| MMR |
20150630 |
|
| MN |
F03.615.400.125 C10.597.606.150.500.800.100.155 C23.888.592.604.150.500.800.100.155 C10.228.140.380.132 |
|
| notation |
D018888 |
|
| prefLabel |
Aphasia, Primary Progressive |
|
| TERMUI |
T056300 T056302 T056301 |
|
| TH |
NLM (1996) OMIM (2013) ORD (2010) |
|
| tui |
T048 |
|
| subClassOf |