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Last uploaded: January 31, 2024

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Preferred Name	Hydroxymethylglutaryl-CoA Reductase Inhibitors
Synonyms	Inhibitors, Hydroxymethylglutaryl CoA Hydroxymethylglutaryl CoA Reductase Inhibitors Inhibitors, Hydroxymethylglutaryl Coenzyme A Hydroxymethylglutaryl-CoA Reductase Inhibitor Inhibitors, HMG-CoA Reductase HMG-CoA Statins Statins Inhibitors, Hydroxymethylglutaryl-CoA HMG CoA Reductase Inhibitors HMG-CoA Reductase Inhibitors Statin Statins, HMG-CoA Hydroxymethylglutaryl-Coenzyme A Inhibitors Inhibitors, HMG CoA Reductase Reductase Inhibitors, HMG-CoA Statins, HMG CoA Inhibitors, Hydroxymethylglutaryl-Coenzyme A Hydroxymethylglutaryl CoA Reductase Inhibitor Reductase Inhibitor, Hydroxymethylglutaryl-CoA Hydroxymethylglutaryl-CoA Inhibitors Inhibitors, Hydroxymethylglutaryl-CoA Reductase HMG CoA Reductase Inhibitor HMG-CoA Reductase Inhibitor Reductase Inhibitors, Hydroxymethylglutaryl-CoA
Definitions	Compounds that inhibit HYDROXYMETHYLGLUTARYL COA REDUCTASES. They have been shown to directly lower CHOLESTEROL synthesis.
ID	http://purl.bioontology.org/ontology/MESH/D019161
altLabel	Inhibitors, Hydroxymethylglutaryl CoA Hydroxymethylglutaryl CoA Reductase Inhibitors Inhibitors, Hydroxymethylglutaryl Coenzyme A Hydroxymethylglutaryl-CoA Reductase Inhibitor Inhibitors, HMG-CoA Reductase HMG-CoA Statins Statins Inhibitors, Hydroxymethylglutaryl-CoA HMG CoA Reductase Inhibitors HMG-CoA Reductase Inhibitors Statin Statins, HMG-CoA Hydroxymethylglutaryl-Coenzyme A Inhibitors Inhibitors, HMG CoA Reductase Reductase Inhibitors, HMG-CoA Statins, HMG CoA Inhibitors, Hydroxymethylglutaryl-Coenzyme A Hydroxymethylglutaryl CoA Reductase Inhibitor Reductase Inhibitor, Hydroxymethylglutaryl-CoA Hydroxymethylglutaryl-CoA Inhibitors Inhibitors, Hydroxymethylglutaryl-CoA Reductase HMG CoA Reductase Inhibitor HMG-CoA Reductase Inhibitor Reductase Inhibitors, Hydroxymethylglutaryl-CoA
AQL	AD AE AN BL CF CH CL CS EC HI IM IP ME PD PK PO RE SD ST TO TU UR
cui	C0360714
DC	1
definition	Compounds that inhibit HYDROXYMETHYLGLUTARYL COA REDUCTASES. They have been shown to directly lower CHOLESTEROL synthesis.
DX	19970101
FX	D006903
HN	98
Inverse of AQ	http://purl.bioontology.org/ontology/MESH/Q000097 http://purl.bioontology.org/ontology/MESH/Q000627 http://purl.bioontology.org/ontology/MESH/Q000493 http://purl.bioontology.org/ontology/MESH/Q000494 http://purl.bioontology.org/ontology/MESH/Q000276 http://purl.bioontology.org/ontology/MESH/Q000138 http://purl.bioontology.org/ontology/MESH/Q000134 http://purl.bioontology.org/ontology/MESH/Q000266 http://purl.bioontology.org/ontology/MESH/Q000378 http://purl.bioontology.org/ontology/MESH/Q000008 http://purl.bioontology.org/ontology/MESH/Q000009 http://purl.bioontology.org/ontology/MESH/Q000032 http://purl.bioontology.org/ontology/MESH/Q000191 http://purl.bioontology.org/ontology/MESH/Q000302 http://purl.bioontology.org/ontology/MESH/Q000145 http://purl.bioontology.org/ontology/MESH/Q000592 http://purl.bioontology.org/ontology/MESH/Q000737 http://purl.bioontology.org/ontology/MESH/Q000506 http://purl.bioontology.org/ontology/MESH/Q000633 http://purl.bioontology.org/ontology/MESH/Q000600 http://purl.bioontology.org/ontology/MESH/Q000652 http://purl.bioontology.org/ontology/MESH/Q000528
Inverse of isa	http://purl.bioontology.org/ontology/MESH/C045196 http://purl.bioontology.org/ontology/MESH/C083011 http://purl.bioontology.org/ontology/MESH/C086156 http://purl.bioontology.org/ontology/MESH/C084394 http://purl.bioontology.org/ontology/MESH/C062437 http://purl.bioontology.org/ontology/MESH/D015093 http://purl.bioontology.org/ontology/MESH/C487936 http://purl.bioontology.org/ontology/MESH/C117343 http://purl.bioontology.org/ontology/MESH/C058117 http://purl.bioontology.org/ontology/MESH/C074570 http://purl.bioontology.org/ontology/MESH/D008148 http://purl.bioontology.org/ontology/MESH/C070474 http://purl.bioontology.org/ontology/MESH/C020857 http://purl.bioontology.org/ontology/MESH/C070543 http://purl.bioontology.org/ontology/MESH/C073202 http://purl.bioontology.org/ontology/MESH/C108475 http://purl.bioontology.org/ontology/MESH/C075612 http://purl.bioontology.org/ontology/MESH/C088576 http://purl.bioontology.org/ontology/MESH/C065178 http://purl.bioontology.org/ontology/MESH/C059132 http://purl.bioontology.org/ontology/MESH/C066279 http://purl.bioontology.org/ontology/MESH/C082797 http://purl.bioontology.org/ontology/MESH/C049114 http://purl.bioontology.org/ontology/MESH/C064146 http://purl.bioontology.org/ontology/MESH/C064145 http://purl.bioontology.org/ontology/MESH/C039122 http://purl.bioontology.org/ontology/MESH/C503947 http://purl.bioontology.org/ontology/MESH/C078005 http://purl.bioontology.org/ontology/MESH/C078004 http://purl.bioontology.org/ontology/MESH/C061276 http://purl.bioontology.org/ontology/MESH/C012258 http://purl.bioontology.org/ontology/MESH/C053475 http://purl.bioontology.org/ontology/MESH/D019821 http://purl.bioontology.org/ontology/MESH/C043447 http://purl.bioontology.org/ontology/MESH/C063286 http://purl.bioontology.org/ontology/MESH/C089703 http://purl.bioontology.org/ontology/MESH/C031380 http://purl.bioontology.org/ontology/MESH/D000068718 http://purl.bioontology.org/ontology/MESH/D000069059 http://purl.bioontology.org/ontology/MESH/C086276 http://purl.bioontology.org/ontology/MESH/C068819 http://purl.bioontology.org/ontology/MESH/C078258 http://purl.bioontology.org/ontology/MESH/C084470 http://purl.bioontology.org/ontology/MESH/C084472 http://purl.bioontology.org/ontology/MESH/C031351 http://purl.bioontology.org/ontology/MESH/C081831 http://purl.bioontology.org/ontology/MESH/C076016 http://purl.bioontology.org/ontology/MESH/C076014 http://purl.bioontology.org/ontology/MESH/C076015 http://purl.bioontology.org/ontology/MESH/C076017 http://purl.bioontology.org/ontology/MESH/C076018 http://purl.bioontology.org/ontology/MESH/D017035
Inverse of RB	0
Inverse of RO	http://purl.bioontology.org/ontology/MESH/D006903
Machine permutation	98; see HMG-COA REDUCTASE INHIBITORS 1997; for HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS see HMG-COA REDUCTASE INHIBITORS 1997
MDA	19960610
MMR	20200527
MN	D27.505.519.186.071.202.370 D27.505.519.389.370 D27.505.954.557.500.202.370
notation	D019161
prefLabel	Hydroxymethylglutaryl-CoA Reductase Inhibitors
TERMUI	T475782 T057152 T057155 T000898304 T057156 T001000456 T057154 T057153 T000996087 T000996796
TH	NLM (1997) NLM (2021) NLM (2003) NLM (1998) NLM (2017)
tui	T109 T121
subClassOf	http://purl.bioontology.org/ontology/MESH/D000924 http://purl.bioontology.org/ontology/MESH/D004791

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Mapping To	Ontology	Source
http://purl.bioontology.org/ontology/SCTSPA/372912004	SCTSPA	CUI
http://purl.bioontology.org/ontology/SCTSPA/96302009	SCTSPA	CUI
http://purl.bioontology.org/ontology/SNMI/C-80800	SNMI	CUI
http://purl.bioontology.org/ontology/MEDLINEPLUS/C0360714	MEDLINEPLUS	CUI
http://purl.bioontology.org/ontology/RCD/x01R1	RCD	CUI
http://purl.bioontology.org/ontology/CSP/0658-5374	CRISP	CUI
http://purl.bioontology.org/ontology/SNOMEDCT/96302009	SNOMEDCT	CUI
http://purl.bioontology.org/ontology/MSHFRE/D019161	MSHFRE	CUI
http://purl.bioontology.org/ontology/SNOMEDCT/372912004	SNOMEDCT	CUI
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D27.505.519.389.370	RH-MESH	LOOM
http://purl.obolibrary.org/obo/MESH_D019161	BERO	LOOM
http://purl.obolibrary.org/obo/OMIT_0019243	OMIT	LOOM
http://id.nlm.nih.gov/mesh/D019161	MDM	LOOM
http://bmi.utah.edu/ontologies/hfontology/C0360714	HFO	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D27.505.954.557.500.202.370	RH-MESH	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D27.505.519.186.071.202.370	RH-MESH	LOOM
http://doe-generated-ontology.com/OntoAD#C0360714	ONTOAD	LOOM
http://www.phoc.org.cn/pmo/class/PMO_00024564	PMAPP-PMO	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D019161	RH-MESH	LOOM