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Last uploaded:
January 16, 2025
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| Id | http://purl.bioontology.org/ontology/MESH/D019578
http://purl.bioontology.org/ontology/MESH/D019578
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|---|---|
| Preferred Name | Multiple System Atrophy |
| Definitions |
A syndrome complex composed of three conditions which represent clinical variants of the same disease process: STRIATONIGRAL DEGENERATION; SHY-DRAGER SYNDROME; and the sporadic form of OLIVOPONTOCEREBELLAR ATROPHIES. Clinical features include autonomic, cerebellar, and basal ganglia dysfunction. Pathologic examination reveals atrophy of the basal ganglia, cerebellum, pons, and medulla, with prominent loss of autonomic neurons in the brain stem and spinal cord. (From Adams et al., Principles of Neurology, 6th ed, p1076; Baillieres Clin Neurol 1997 Apr;6(1):187-204; Med Clin North Am 1999 Mar;83(2):381-92)
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| Synonyms |
Atrophy, Multisystemic
Atrophies, Multisystem
Multisystem Atrophy
Multisystemic Atrophies
Multisystemic Atrophy
Atrophies, Multisystemic
Atrophy, Multiple System
Multiple System Atrophy Syndrome
Multiple System Atrophies
Multisystem Atrophies
Atrophy, Multisystem
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|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A syndrome complex composed of three conditions which represent clinical variants of the same disease process: STRIATONIGRAL DEGENERATION; SHY-DRAGER SYNDROME; and the sporadic form of OLIVOPONTOCEREBELLAR ATROPHIES. Clinical features include autonomic, cerebellar, and basal ganglia dysfunction. Pathologic examination reveals atrophy of the basal ganglia, cerebellum, pons, and medulla, with prominent loss of autonomic neurons in the brain stem and spinal cord. (From Adams et al., Principles of Neurology, 6th ed, p1076; Baillieres Clin Neurol 1997 Apr;6(1):187-204; Med Clin North Am 1999 Mar;83(2):381-92) |
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| altLabel |
Atrophy, Multisystemic
Atrophies, Multisystem
Multisystem Atrophy
Multisystemic Atrophies
Multisystemic Atrophy
Atrophies, Multisystemic
Atrophy, Multiple System
Multiple System Atrophy Syndrome
Multiple System Atrophies
Multisystem Atrophies
Atrophy, Multisystem
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| prefLabel | Multiple System Atrophy
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| TH |
OMIM (2013)
NLM (2000)
GHR (2014)
NLM (1998)
ORD (2010)
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| notation | D019578
|
| DX | 19980101
|
| Machine permutation | 1998
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| MN |
C10.228.140.079.612
C10.574.928.625
C10.177.575.550
C10.228.662.550
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| FX |
D009849
D012791
|
| MMR | 20190517
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| Mapped from | |
| AQL | BL CF CI CL CN CO DG DH DI DT EC EH EM EN EP ET GE HI IM ME MI MO NU PA PC PP PS PX RH RT SU TH UR VE VI
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| HN | 1998
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| subClassOf | |
| Semantic type UMLS property | |
| DC | 1
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| MDA | 19970620
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| Inverse of RO | |
| type | |
| tui | T046
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| cui | C0393571
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| AN | a specific neurodegenerative syndrome complex; not for atrophy in other systems
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| Inverse of AQ |
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| TERMUI |
T364299
T364305
T058282
T364298
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