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Medical Subject Headings
Last uploaded:
January 16, 2025
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| Id | http://purl.bioontology.org/ontology/MESH/D019943
http://purl.bioontology.org/ontology/MESH/D019943
|
|---|---|
| Preferred Name | Amino Acid Substitution |
| Definitions |
The naturally occurring or experimentally induced replacement of one or more AMINO ACIDS in a protein with another. If a functionally equivalent amino acid is substituted, the protein may retain wild-type activity. Substitution may also diminish, enhance, or eliminate protein function. Experimentally induced substitution is often used to study enzyme activities and binding site properties.
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| Synonyms |
Amino Acid Substitutions
Substitutions, Amino Acid
Substitution, Amino Acid
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | The naturally occurring or experimentally induced replacement of one or more AMINO ACIDS in a protein with another. If a functionally equivalent amino acid is substituted, the protein may retain wild-type activity. Substitution may also diminish, enhance, or eliminate protein function. Experimentally induced substitution is often used to study enzyme activities and binding site properties. |
|---|---|
| altLabel |
Amino Acid Substitutions
Substitutions, Amino Acid
Substitution, Amino Acid
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| prefLabel | Amino Acid Substitution
|
| TH | NLM (1998)
|
| notation | D019943
|
| DX | 19980101
|
| Machine permutation | 98
|
| MN |
E05.393.420.601.035
G05.558.109
|
| FX |
D016297
D020125
|
| MMR | 20160115
|
| AQL | DE GE IM PH RE
|
| HN | 98
|
| subClassOf | |
| Semantic type UMLS property | |
| DC | 1
|
| MDA | 19970620
|
| Inverse of RO | |
| type | |
| tui | T045
|
| cui | C0525038
|
| Inverse of AQ | |
| TERMUI | T059440
|
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