Medical Subject Headings

Last uploaded: January 16, 2025
Id http://purl.bioontology.org/ontology/MESH/D047888
http://purl.bioontology.org/ontology/MESH/D047888
Preferred Name

Receptors, Tumor Necrosis Factor, Type I

Definitions
A tumor necrosis factor receptor subtype that has specificity for TUMOR NECROSIS FACTOR ALPHA and LYMPHOTOXIN ALPHA. It is constitutively expressed in most tissues and is a key mediator of tumor necrosis factor signaling in the vast majority of cells. The activated receptor signals via a conserved death domain that associates with specific TNF RECEPTOR-ASSOCIATED FACTORS in the CYTOPLASM.
Synonyms
TNFR p60
Receptors, Tumor Necrosis Factor, Member 1A
TNFR1
Antigen, CD 120a
TNFRSF1A (Tumor Necrosis Factor Receptor Superfamily, Member 1A)
CD 120a Antigen
Tumor Necrosis Factor Receptor Superfamily, Member 1A
Antigens, CD120a
TNFRSF1A Receptor
TNFR-I
CD120a Antigens
CD120a Antigen
Receptor, TNFRSF1A
120a Antigen, CD
Tumor Necrosis Factor Receptor Type I
Tumor Necrosis Factor Receptor Type 1
Antigen, CD120a
Tumor Necrosis Factor Receptor 1A
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Type http://www.w3.org/2002/07/owl#Class
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