A large family of structurally-related transcription factors that were originally discovered based upon their close sequence homology to an HMG-box domain found in SEX-DETERMINING REGION Y PROTEIN. Many SOX transcription factors play important roles in regulating CELL DIFFERENTIATION. The numerous members of this family are organized in several subgroups according to structural identities found within the proteins.
ID
http://purl.bioontology.org/ontology/MESH/D055747
altLabel
Transcription Factors, SOX
SOX Family of Transcription Factors
SRY (Sex Determining Region Y)-Box Proteins
SOX Transcription Factor Family
AN
do not confuse entry term SRY (SEX DETERMINING REGION Y)-BOX PROTEINS with SRY SEX-DETERMINING REGION PROTEIN see SEX-DETERMINING REGION Y PROTEIN
AQL
AD AE AG AI AN BI BL CF CH CL CS DE DF EC GE HI IM IP ME PD PH PK PO RE SD ST TO TU UL UR
cui
C2350532
DC
1
definition
A large family of structurally-related transcription factors that were originally discovered based upon their close sequence homology to an HMG-box domain found in SEX-DETERMINING REGION Y PROTEIN. Many SOX transcription factors play important roles in regulating CELL DIFFERENTIATION. The numerous members of this family are organized in several subgroups according to structural identities found within the proteins.