| altLabel |
Primary Senile Degenerative Dementia Alzheimer's Disease Alzheimer Dementia (AD) Alzheimer-Type Dementia (ATD) Alzheimer Syndrome Dementia, Alzheimer Type Dementia, Primary Senile Degenerative Dementia, Senile Alzheimer Type Senile Dementia Senile Dementia, Alzheimer Type Alzheimer Sclerosis Alzheimer Disease
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| MESH DEFINITION |
A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57)
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