loading...| Preferred Name |
Rifampin [Chemical/Ingredient] |
|
| Synonyms |
Rifampicin Benemycin |
|
| ID |
http://purl.bioontology.org/ontology/NDFRT/N0000006026 |
|
| altLabel |
Rifampicin Rifamycin, 3-(((4-methyl-1-piperazinyl)imino)methyl)- Rifampin Benemycin |
|
| Contraindicating class of |
http://purl.bioontology.org/ontology/NDFRT/N0000163931 http://purl.bioontology.org/ontology/NDFRT/N0000163932 http://purl.bioontology.org/ontology/NDFRT/N0000163934 http://purl.bioontology.org/ontology/NDFRT/N0000148609 |
|
| cui |
C0035608 |
|
| Ingredient of |
http://purl.bioontology.org/ontology/NDFRT/N0000020462 http://purl.bioontology.org/ontology/NDFRT/N0000021961 http://purl.bioontology.org/ontology/NDFRT/N0000153686 http://purl.bioontology.org/ontology/NDFRT/N0000160413 http://purl.bioontology.org/ontology/NDFRT/N0000153688 http://purl.bioontology.org/ontology/NDFRT/N0000153685 |
|
| MESH DEFINITION |
A semisynthetic antibiotic produced from Streptomyces mediterranei. It has a broad antibacterial spectrum, including activity against several forms of Mycobacterium. In susceptible organisms it inhibits DNA-dependent RNA polymerase activity by forming a stable complex with the enzyme. It thus suppresses the initiation of RNA synthesis. Rifampin is bactericidal, and acts on both intracellular and extracellular organisms. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p1160) |
|
| MESH DUI |
D012293 |
|
| MeSH name |
Rifampin |
|
| MESH UI |
M0019110 |
|
| NDFRT kind |
INGREDIENT_KIND |
|
| notation |
N0000006026 |
|
| NUI |
N0000006026 |
|
| prefLabel |
Rifampin [Chemical/Ingredient] |
|
| tui |
T109 T195 |
|
| subClassOf |