loading...| Preferred Name |
Ivermectin [Chemical/Ingredient] |
|
| Synonyms |
Ivermectin |
|
| ID |
http://purl.bioontology.org/ontology/NDFRT/N0000006374 |
|
| altLabel |
Ivermectin |
|
| cui |
C0022322 |
|
| Ingredient of |
http://purl.bioontology.org/ontology/NDFRT/N0000184586 http://purl.bioontology.org/ontology/NDFRT/N0000191370 |
|
| MESH DEFINITION |
A mixture of mostly avermectin H2B1a (RN 71827-03-7) with some avermectin H2B1b (RN 70209-81-3), which are macrolides from STREPTOMYCES avermitilis. It binds glutamate-gated chloride channel to cause increased permeability and hyperpolarization of nerve and muscle cells. It also interacts with other CHLORIDE CHANNELS. It is a broad spectrum antiparasitic that is active against microfilariae of ONCHOCERCA VOLVULUS but not the adult form. |
|
| MESH DUI |
D007559 |
|
| MeSH name |
Ivermectin |
|
| MESH UI |
M0011815 |
|
| NDFRT kind |
INGREDIENT_KIND |
|
| notation |
N0000006374 |
|
| NUI |
N0000006374 |
|
| prefLabel |
Ivermectin [Chemical/Ingredient] |
|
| tui |
T109 T121 |
|
| subClassOf |