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loading...| Preferred Name |
Dactinomycin [Chemical/Ingredient] |
|
| Synonyms |
Actinomycin D |
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| ID |
http://purl.bioontology.org/ontology/NDFRT/N0000006852 |
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| altLabel |
Actinomycin D Meractinomycin Dactinomycin |
|
| cui |
C0010934 |
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| Ingredient of | ||
| MESH DEFINITION |
A compound composed of a two CYCLIC PEPTIDES attached to a phenoxazine that is derived from STREPTOMYCES parvullus. It binds to DNA and inhibits RNA synthesis (transcription), with chain elongation more sensitive than initiation, termination, or release. As a result of impaired mRNA production, protein synthesis also declines after dactinomycin therapy. (From AMA Drug Evaluations Annual, 1993, p2015) |
|
| MESH DUI |
D003609 |
|
| MeSH name |
Dactinomycin |
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| MESH UI |
M0005644 |
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| NDFRT kind |
INGREDIENT_KIND |
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| notation |
N0000006852 |
|
| NUI |
N0000006852 |
|
| prefLabel |
Dactinomycin [Chemical/Ingredient] |
|
| tui |
T195 T116 |
|
| subClassOf |
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