National Drug File - Reference Terminology

Last uploaded: July 6, 2018
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Id http://purl.bioontology.org/ontology/NDFRT/N0000007302
http://purl.bioontology.org/ontology/NDFRT/N0000007302
Preferred Name

Tacrolimus [Chemical/Ingredient]
Synonyms
15,19-Epoxy-3H-pyrido(2,1-c)(1,4)oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone, 5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-5,19-dihydroxy-3-(2-(4-hydroxy-3-methoxycyclohexyl)-1-methylethenyl)-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-p
Tacrolimus
Type http://www.w3.org/2002/07/owl#Class

All Properties

altLabel
15,19-Epoxy-3H-pyrido(2,1-c)(1,4)oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone, 5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-5,19-dihydroxy-3-(2-(4-hydroxy-3-methoxycyclohexyl)-1-methylethenyl)-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-p
Tacrolimus
prefLabel
Tacrolimus [Chemical/Ingredient]
notation
N0000007302
MESH DEFINITION
A macrolide isolated from the culture broth of a strain of Streptomyces tsukubaensis that has strong immunosuppressive activity in vivo and prevents the activation of T-lymphocytes in response to antigenic or mitogenic stimulation in vitro.
MESH UI
M0025261
subClassOf
Semantic type UMLS property
MeSH name
Tacrolimus
NDFRT kind
INGREDIENT_KIND
type
tui
T109
T121
NUI
N0000007302
cui
C0085149
Ingredient of
MESH DUI
D016559
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