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National Drug File - Reference Terminology
Last uploaded:
July 6, 2018
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| Id | http://purl.bioontology.org/ontology/NDFRT/N0000007622
http://purl.bioontology.org/ontology/NDFRT/N0000007622
|
|---|---|
| Preferred Name | Mycophenolic Acid [Chemical/Ingredient] |
| Synonyms |
-Hexenoic acid, 6-(1,3-dihydro-4-hydroxy-6-methoxy-7-methyl-3-oxo-5-isobenzofuranyl)-4-methyl-, (E)-
Mycophenolic Acid
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| altLabel | -Hexenoic acid, 6-(1,3-dihydro-4-hydroxy-6-methoxy-7-methyl-3-oxo-5-isobenzofuranyl)-4-methyl-, (E)-
Mycophenolic Acid
|
|---|---|
| prefLabel | Mycophenolic Acid [Chemical/Ingredient]
|
| notation | N0000007622
|
| MESH DEFINITION | Compound derived from Penicillium stoloniferum and related species. It blocks de novo biosynthesis of purine nucleotides by inhibition of the enzyme inosine monophosphate dehydrogenase (IMP DEHYDROGENASE). Mycophenolic acid exerts selective effects on the immune system in which it prevents the proliferation of T-CELLS, LYMPHOCYTES, and the formation of antibodies from B-CELLS. It may also inhibit recruitment of LEUKOCYTES to sites of INFLAMMATION.
|
| MESH UI | M0014304
|
| subClassOf | |
| Semantic type UMLS property | |
| MeSH name | Mycophenolic Acid
|
| NDFRT kind | INGREDIENT_KIND
|
| type | |
| tui |
T109
T195
|
| NUI | N0000007622
|
| cui | C0026933
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| MESH DUI | D009173
|
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