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National Drug File - Reference Terminology
Last uploaded:
July 6, 2018
Acronym | NDFRT |
Visibility | Public |
Description | National Drug File - Reference Terminology Public Inferred Edition, 2008_03_11 |
Status | Production |
Format | UMLS |
Contact | Michael J. Lincoln MD, michael.lincoln@va.gov |
Categories | Health |
Groups | Unified Medical Language System |
License Information | This ontology is made available via the UMLS. Users of all UMLS ontologies must abide by the terms of the UMLS license. |
Version | Released | Uploaded |
---|---|---|
NDFRT_2018_02_05_18_03_05 (Parsed, Indexed, Metrics, Annotator, Error Diff) | 05/07/2018 | 07/06/2018 |
2017AB (Archived) | 11/06/2017 | 07/06/2018 |
2017AA (Archived) | 05/08/2017 | 04/06/2018 |
2016AB (Archived) | 02/06/2017 | 02/06/2017 |
2016AA (Archived) | 09/06/2016 | 09/06/2016 |
2015AB (Archived) | 07/20/2016 | 07/20/2016 |
2015AA (Archived) | 06/09/2015 | 06/09/2015 |
2014AB (Archived) | 01/29/2015 | 01/29/2015 |
2014AA (Archived) | 05/28/2014 | 05/28/2014 |
2013AB (Archived) | 02/18/2014 | 02/18/2014 |
2013AA (Archived) | 01/14/2014 | 01/14/2014 |
2013AA (Archived) | 05/08/2013 | 09/25/2013 |
2008_03_11 (Archived) | 03/11/2008 | 07/31/2009 |
more... |
- National Drug File – Reference Terminology
- Logically inferred version in OWL of the National Drug File – Reference Terminology (NDF-RT). NDF-RT is the terminology used by FDA and the FedMed collaboration to code these essential pharmacologic properties of medications: Mechanism of Action, Physiologic Effect, Structural Class.
Classes | 36,202 |
Individuals | 0 |
Properties | 53 |
Maximum depth | 11 |
Maximum number of children | 953 |
Average number of children | 3 |
Classes with a single child | 4,051 |
Classes with more than 25 children | 87 |
Classes with no definition | 36,171 |
Jump to:
Id | http://purl.bioontology.org/ontology/NDFRT/N0000008157
http://purl.bioontology.org/ontology/NDFRT/N0000008157
|
---|---|
Preferred Name | Cardiac Glycosides [Chemical/Ingredient] |
Synonyms |
Cardiac Glycosides
Cardiotonic Steroids
|
Type | http://www.w3.org/2002/07/owl#Class |
All Properties
altLabel |
Cardiac Glycosides
Cardiotonic Steroids
|
---|---|
prefLabel |
Cardiac Glycosides [Chemical/Ingredient]
|
notation |
N0000008157
|
MESH DEFINITION |
Cyclopentanophenanthrenes with a 5- or 6-membered lactone ring attached at the 17-position and SUGARS attached at the 3-position. Plants they come from have long been used in congestive heart failure. They increase the force of cardiac contraction without significantly affecting other parameters, but are very toxic at larger doses. Their mechanism of action usually involves inhibition of the NA(+)-K(+)-EXCHANGING ATPASE and they are often used in cell biological studies for that purpose.
|
MESH UI |
M0003451
|
subClassOf | |
Semantic type UMLS property | |
MeSH name |
Cardiac Glycosides
|
NDFRT kind |
INGREDIENT_KIND
|
type | |
tui |
T109
T121
|
NUI |
N0000008157
|
cui |
C0007158
|
MESH DUI |
D002301
|
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