Preferred Name

Meglutol [Chemical/Ingredient]

Synonyms

3-Hydroxy-3-methylglutaric Acid

ID

http://purl.bioontology.org/ontology/NDFRT/N0000166734

altLabel

3-Hydroxy-3-methylglutaric Acid

3-Hydroxy-3-methylpentanedioic Acid

beta-Hydroxy-beta-Methylglutarate

Meglutol

Pentanedioic acid, 3-hydroxy-3-methyl-

cui

C0000402

MESH DEFINITION

An antilipemic agent which lowers cholesterol, triglycerides, serum beta-lipoproteins and phospholipids. It acts by interfering with the enzymatic steps involved in the conversion of acetate to hydroxymethylglutaryl coenzyme A as well as inhibiting the activity of HYDROXYMETHYLGLUTARYL COA REDUCTASES which is the rate limiting enzyme in the biosynthesis of cholesterol.

MESH DUI

D015093

MeSH name

Meglutol

MESH UI

M0023214

NDFRT kind

INGREDIENT_KIND

notation

N0000166734

NUI

N0000166734

prefLabel

Meglutol [Chemical/Ingredient]

tui

T109

T121

subClassOf

http://purl.bioontology.org/ontology/NDFRT/N0000166731

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