Preferred Name

1-Methyl-4-phenylpyridinium [Chemical/Ingredient]

Synonyms

Cyperquat

ID

http://purl.bioontology.org/ontology/NDFRT/N0000167230

altLabel

Cyperquat

Pyridinium, 1-methyl-4-phenyl-

1-Methyl-4-phenylpyridinium

1-Methyl-4-phenylpyridinium Ion

N-Methyl-4-phenylpyridine

1-Methyl-4-phenylpyridine

N-Methyl-4-phenylpyridinium

cui

C0000098

MESH DEFINITION

An active neurotoxic metabolite of 1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE. The compound reduces dopamine levels, inhibits the biosynthesis of catecholamines, depletes cardiac norepinephrine and inactivates tyrosine hydroxylase. These and other toxic effects lead to cessation of oxidative phosphorylation, ATP depletion, and cell death. The compound, which is related to PARAQUAT, has also been used as an herbicide.

MESH DUI

D015655

MeSH name

1-Methyl-4-phenylpyridinium

MESH UI

M0023993

NDFRT kind

INGREDIENT_KIND

notation

N0000167230

NUI

N0000167230

prefLabel

1-Methyl-4-phenylpyridinium [Chemical/Ingredient]

tui

T109

T131

subClassOf

http://purl.bioontology.org/ontology/NDFRT/N0000007571

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