loading...| Preferred Name |
Picrotoxin [Chemical/Ingredient] |
|
| Synonyms |
3,6-Methano-8H-1,5,7-trioxacyclopenta(ij)cycloprop(a)azulene-4,8(3H)-dione, hexahydro-2a-hydroxy-9-(1-hydroxy-1-methylethyl)-8b-methyl-, (1aR-(1aalpha,2abeta,3beta,6beta,6abeta,8aS*,8bbeta,9S*))-, compd. with (1aR-(1aalpha,2abeta,3beta,6beta,6abeta,8aS*,8 |
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| ID |
http://purl.bioontology.org/ontology/NDFRT/N0000168439 |
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| altLabel |
3,6-Methano-8H-1,5,7-trioxacyclopenta(ij)cycloprop(a)azulene-4,8(3H)-dione, hexahydro-2a-hydroxy-9-(1-hydroxy-1-methylethyl)-8b-methyl-, (1aR-(1aalpha,2abeta,3beta,6beta,6abeta,8aS*,8bbeta,9S*))-, compd. with (1aR-(1aalpha,2abeta,3beta,6beta,6abeta,8aS*,8 Picrotoxin |
|
| cui |
C0031890 |
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| MESH DEFINITION |
A noncompetitive antagonist at GABA-A receptors and thus a convulsant. Picrotoxin blocks the GAMMA-AMINOBUTYRIC ACID-activated chloride ionophore. Although it is most often used as a research tool, it has been used as a CNS stimulant and an antidote in poisoning by CNS depressants, especially the barbiturates. |
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| MESH DUI |
D010852 |
|
| MeSH name |
Picrotoxin |
|
| MESH UI |
M0016843 |
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| NDFRT kind |
INGREDIENT_KIND |
|
| notation |
N0000168439 |
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| NUI |
N0000168439 |
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| prefLabel |
Picrotoxin [Chemical/Ingredient] |
|
| tui |
T109 T131 T121 |
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| subClassOf |