Preferred Name

12-Hydroxy-5,8,10,14-eicosatetraenoic Acid [Chemical/Ingredient]

Synonyms

12-HETE

ID

http://purl.bioontology.org/ontology/NDFRT/N0000168586

altLabel

12-HETE

12-Hydroxy-5,8,10,14-eicosatetraenoic Acid

cui

C0044800

MESH DEFINITION

A lipoxygenase metabolite of ARACHIDONIC ACID. It is a highly selective ligand used to label mu-opioid receptors in both membranes and tissue sections. The 12-S-HETE analog has been reported to augment tumor cell metastatic potential through activation of protein kinase C. (J Pharmacol Exp Ther 1995; 274(3):1545-51; J Natl Cancer Inst 1994; 86(15):1145-51)

MESH DUI

D019377

MeSH name

12-Hydroxy-5,8,10,14-eicosatetraenoic Acid

MESH UI

M0028832

NDFRT kind

INGREDIENT_KIND

notation

N0000168586

NUI

N0000168586

prefLabel

12-Hydroxy-5,8,10,14-eicosatetraenoic Acid [Chemical/Ingredient]

tui

T109

T123

subClassOf

http://purl.bioontology.org/ontology/NDFRT/N0000168585

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