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National Drug File - Reference Terminology
Last uploaded:
July 6, 2018
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Id | http://purl.bioontology.org/ontology/NDFRT/N0000169116
http://purl.bioontology.org/ontology/NDFRT/N0000169116
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Preferred Name | Prions [Chemical/Ingredient] |
Synonyms |
Prions
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Type | http://www.w3.org/2002/07/owl#Class |
All Properties
altLabel | Prions
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prefLabel | Prions [Chemical/Ingredient]
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notation | N0000169116
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MESH DEFINITION | Small proteinaceous infectious particles which resist inactivation by procedures that modify NUCLEIC ACIDS and contain an abnormal isoform of a cellular protein which is a major and necessary component. The abnormal (scrapie) isoform is PrPSc (PRPSC PROTEINS) and the cellular isoform PrPC (PRPC PROTEINS). The primary amino acid sequence of the two isoforms is identical. Human diseases caused by prions include CREUTZFELDT-JAKOB SYNDROME; GERSTMANN-STRAUSSLER SYNDROME; and INSOMNIA, FATAL FAMILIAL.
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MESH UI | M0017586
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subClassOf | |
Semantic type UMLS property | |
MeSH name | Prions
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NDFRT kind | INGREDIENT_KIND
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type | |
tui | T116
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NUI | N0000169116
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cui | C0033164
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MESH DUI | D011328
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