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National Drug File - Reference Terminology
Last uploaded:
July 6, 2018
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| Id | http://purl.bioontology.org/ontology/NDFRT/N0000169370
http://purl.bioontology.org/ontology/NDFRT/N0000169370
|
|---|---|
| Preferred Name | Antibodies, Bispecific [Chemical/Ingredient] |
| Synonyms |
Bifunctional Antibodies
Bispecific Antibodies
Antibodies, Bispecific
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| altLabel |
Bifunctional Antibodies
Bispecific Antibodies
Antibodies, Bispecific
|
|---|---|
| prefLabel | Antibodies, Bispecific [Chemical/Ingredient]
|
| notation | N0000169370
|
| MESH DEFINITION | Antibodies, often monoclonal, in which the two antigen-binding sites are specific for separate ANTIGENIC DETERMINANTS. They are artificial antibodies produced by chemical crosslinking, fusion of HYBRIDOMA cells, or by molecular genetic techniques. They function as the main mediators of targeted cellular cytotoxicity and have been shown to be efficient in the targeting of drugs, toxins, radiolabeled haptens, and effector cells to diseased tissue, primarily tumors.
|
| MESH UI | M0027219
|
| subClassOf | |
| Semantic type UMLS property | |
| MeSH name | Antibodies, Bispecific
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| NDFRT kind | INGREDIENT_KIND
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| type | |
| tui |
T116
T129
T121
|
| NUI | N0000169370
|
| cui | C0206492
|
| MESH DUI | D018033
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