loading...| Preferred Name |
Aromatase [Chemical/Ingredient] |
|
| Synonyms |
P450AROM |
|
| ID |
http://purl.bioontology.org/ontology/NDFRT/N0000170034 |
|
| altLabel |
P450AROM CYP19 Protein Cytochrome P450 19 CYP19 Aromatase Cytochrome P-450 CYP19 CYP 19 Cytochrome P-450(AROM) Androstenedione Aromatase Estrogen Synthetase Estrogen Synthase |
|
| cui |
C0003805 |
|
| MESH DEFINITION |
An enzyme that catalyzes the desaturation (aromatization) of the ring A of C19 androgens and converts them to C18 estrogens. In this process, the 19-methyl is removed. This enzyme is membrane-bound, located in the endoplasmic reticulum of estrogen-producing cells of ovaries, placenta, testes, adipose, and brain tissues. Aromatase is encoded by the CYP19 gene, and functions in complex with NADPH-FERRIHEMOPROTEIN REDUCTASE in the cytochrome P-450 system. |
|
| MESH DUI |
D001141 |
|
| MeSH name |
Aromatase |
|
| MESH UI |
M0001707 |
|
| NDFRT kind |
INGREDIENT_KIND |
|
| notation |
N0000170034 |
|
| NUI |
N0000170034 |
|
| prefLabel |
Aromatase [Chemical/Ingredient] |
|
| tui |
T116 T126 |
|
| subClassOf |