loading...| Preferred Name |
Steroid 11-beta-Hydroxylase [Chemical/Ingredient] |
|
| Synonyms |
Cytochrome P450 11B1 |
|
| ID |
http://purl.bioontology.org/ontology/NDFRT/N0000170037 |
|
| altLabel |
Cytochrome P450 11B1 Steroid-11-Hydroxylase Cytochrome P-450 CYP11B1 11 beta-Hydroxylase Cytochrome P-450(11 beta) Steroid 11-beta-Hydroxylase Steroid, reduced-adrenal-ferredoxin:oxygen oxidoreductase (11 beta-hydroxylating) Steroid 11-Hydroxylase Steroid 11 Hydroxylase Steroid 11-beta-Monooxygenase CYP11B1 CYP 11B1 |
|
| cui |
C0038296 |
|
| MESH DEFINITION |
A mitochondrial cytochrome P450 enzyme that catalyzes the 11-beta-hydroxylation of steroids in the presence of molecular oxygen and NADPH-FERRIHEMOPROTEIN REDUCTASE. This enzyme, encoded by CYP11B1 gene, is important in the synthesis of CORTICOSTERONE and HYDROCORTISONE. Defects in CYP11B1 cause congenital adrenal hyperplasia (ADRENAL HYPERPLASIA, CONGENITAL). |
|
| MESH DUI |
D013252 |
|
| MeSH name |
Steroid 11-beta-Hydroxylase |
|
| MESH UI |
M0020521 |
|
| NDFRT kind |
INGREDIENT_KIND |
|
| notation |
N0000170037 |
|
| NUI |
N0000170037 |
|
| prefLabel |
Steroid 11-beta-Hydroxylase [Chemical/Ingredient] |
|
| tui |
T116 T126 |
|
| subClassOf |