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National Drug File - Reference Terminology
Last uploaded:
July 6, 2018
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| Id | http://purl.bioontology.org/ontology/NDFRT/N0000170713
http://purl.bioontology.org/ontology/NDFRT/N0000170713
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|---|---|
| Preferred Name | MicroRNAs [Chemical/Ingredient] |
| Synonyms |
Micro RNA
miRNA
miRNAs
MicroRNA
MicroRNAs
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| altLabel |
Micro RNA
miRNA
miRNAs
MicroRNA
MicroRNAs
|
|---|---|
| prefLabel | MicroRNAs [Chemical/Ingredient]
|
| notation | N0000170713
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| MESH DEFINITION | Small double-stranded, non-protein coding RNAs, 21-25 nucleotides in length generated from single-stranded microRNA gene transcripts by the same RIBONUCLEASE III, Dicer, that produces small interfering RNAs (RNA, SMALL INTERFERING). They become part of the RNA-INDUCED SILENCING COMPLEX and repress the translation (TRANSLATION, GENETIC) of target RNA by binding to homologous 3'UTR region as an imperfect match. The small temporal RNAs (stRNAs), let-7 and lin-4, from C. elegans, are the first 2 miRNAs discovered, and are from a class of miRNAs involved in developmental timing.
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| MESH UI | M0407989
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| subClassOf | |
| Semantic type UMLS property | |
| MeSH name | MicroRNAs
|
| NDFRT kind | INGREDIENT_KIND
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| type | |
| tui |
T123
T114
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| NUI | N0000170713
|
| cui | C1101610
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| MESH DUI | D035683
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