Preferred Name |
Rioprostil [Chemical/Ingredient] |
|
Synonyms |
Prost-13-en-9-one, 1,11,16-trihydroxy-16-methyl-, (11alpha,13E)- |
|
ID |
http://purl.bioontology.org/ontology/NDFRT/N0000171022 |
|
altLabel |
Prost-13-en-9-one, 1,11,16-trihydroxy-16-methyl-, (11alpha,13E)- Rioprostil |
|
cui |
C0085199 |
|
MESH DEFINITION |
A synthetic methylprostaglandin E1 analog that reduces gastric acid secretion and enhances the gastric mucus-bicarbonate barrier. It is effective in the therapy of gastric ulcers and gives significant protection against NSAID-induced gastric mucosal damage. The drug also prevents cyclosporin A-induced damage to endocrine and exocrine pancreatic secretions. It shows a low order of acute toxicity and there is no evidence of embryotoxicity, fetotoxicity, teratogenicity, or mutagenicity in animal studies. |
|
MESH DUI |
D016630 |
|
MeSH name |
Rioprostil |
|
MESH UI |
M0025346 |
|
NDFRT kind |
INGREDIENT_KIND |
|
notation |
N0000171022 |
|
NUI |
N0000171022 |
|
prefLabel |
Rioprostil [Chemical/Ingredient] |
|
tui |
T109 T121 |
|
subClassOf |
Delete | Mapping To | Ontology | Source |
---|---|---|---|
http://purl.bioontology.org/ontology/MESH/D016630 | MESH | CUI | |
http://purl.bioontology.org/ontology/MSHFRE/D016630 | MSHFRE | CUI |