Preferred Name |
Leukotriene A4 [Chemical/Ingredient] |
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Synonyms |
Leukotriene A-4 |
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ID |
http://purl.bioontology.org/ontology/NDFRT/N0000171045 |
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altLabel |
Leukotriene A-4 LTA4 Leukotriene A4 |
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cui |
C0125631 |
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MESH DEFINITION |
(2S-(2 alpha,3 beta(1E,3E,5Z,8Z)))-3-(1,3,5,8-Tetradecatetraenyl)oxiranebutanoic acid. An unstable allylic epoxide, formed from the immediate precursor 5-HPETE via the stereospecific removal of a proton at C-10 and dehydration. Its biological actions are determined primarily by its metabolites, i.e., LEUKOTRIENE B4 and cysteinyl-leukotrienes. Alternatively, leukotriene A4 is converted into LEUKOTRIENE C4 by glutathione-S-transferase or into 5,6-di-HETE by the epoxide-hydrolase. (From Dictionary of Prostaglandins and Related Compounds, 1990) |
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MESH DUI |
D017572 |
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MeSH name |
Leukotriene A4 |
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MESH UI |
M0026633 |
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NDFRT kind |
INGREDIENT_KIND |
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notation |
N0000171045 |
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NUI |
N0000171045 |
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prefLabel |
Leukotriene A4 [Chemical/Ingredient] |
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tui |
T109 T123 |
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subClassOf |