Preferred Name

Leukotriene A4 [Chemical/Ingredient]

Synonyms

Leukotriene A-4

ID

http://purl.bioontology.org/ontology/NDFRT/N0000171045

altLabel

Leukotriene A-4

LTA4

Leukotriene A4

cui

C0125631

MESH DEFINITION

(2S-(2 alpha,3 beta(1E,3E,5Z,8Z)))-3-(1,3,5,8-Tetradecatetraenyl)oxiranebutanoic acid. An unstable allylic epoxide, formed from the immediate precursor 5-HPETE via the stereospecific removal of a proton at C-10 and dehydration. Its biological actions are determined primarily by its metabolites, i.e., LEUKOTRIENE B4 and cysteinyl-leukotrienes. Alternatively, leukotriene A4 is converted into LEUKOTRIENE C4 by glutathione-S-transferase or into 5,6-di-HETE by the epoxide-hydrolase. (From Dictionary of Prostaglandins and Related Compounds, 1990)

MESH DUI

D017572

MeSH name

Leukotriene A4

MESH UI

M0026633

NDFRT kind

INGREDIENT_KIND

notation

N0000171045

NUI

N0000171045

prefLabel

Leukotriene A4 [Chemical/Ingredient]

tui

T109

T123

subClassOf

http://purl.bioontology.org/ontology/NDFRT/N0000171039

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