loading...| Preferred Name |
Aflatoxin B1 [Chemical/Ingredient] |
|
| Synonyms |
Aflatoxin B1 |
|
| ID |
http://purl.bioontology.org/ontology/NDFRT/N0000171418 |
|
| altLabel |
Aflatoxin B1 Cyclopenta(c)furo(3',2':4,5)furo(2,3-h)(1)benzopyran-1,11-dione, 2,3,6a,9a-tetrahydro-4-methoxy-, (6aR-cis)- |
|
| cui |
C0085180 |
|
| MESH DEFINITION |
A potent hepatotoxic and hepatocarcinogenic mycotoxin produced by the Aspergillus flavus group of fungi. It is also mutagenic, teratogenic, and causes immunosuppression in animals. It is found as a contaminant in peanuts, cottonseed meal, corn, and other grains. The mycotoxin requires epoxidation to aflatoxin B1 2,3-oxide for activation. Microsomal monooxygenases biotransform the toxin to the less toxic metabolites aflatoxin M1 and Q1. |
|
| MESH DUI |
D016604 |
|
| MeSH name |
Aflatoxin B1 |
|
| MESH UI |
M0025321 |
|
| NDFRT kind |
INGREDIENT_KIND |
|
| notation |
N0000171418 |
|
| NUI |
N0000171418 |
|
| prefLabel |
Aflatoxin B1 [Chemical/Ingredient] |
|
| tui |
T109 T131 |
|
| subClassOf |