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National Drug File - Reference Terminology
Last uploaded:
July 6, 2018
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| Id | http://purl.bioontology.org/ontology/NDFRT/N0000193060
http://purl.bioontology.org/ontology/NDFRT/N0000193060
|
|---|---|
| Preferred Name | Beclin-1 [Chemical/Ingredient] |
| Synonyms |
GT197 Protein
Coiled-coil Myosin-like Bcl2-interacting Protein
Beclin1
ATG-6 Protein
Beclin-1
Beclin-1 Protein
ATG6 Protein
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| altLabel |
GT197 Protein
Coiled-coil Myosin-like Bcl2-interacting Protein
Beclin1
ATG-6 Protein
Beclin-1
Beclin-1 Protein
ATG6 Protein
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|
|---|---|
| prefLabel |
Beclin-1 [Chemical/Ingredient]
|
| notation |
N0000193060
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| MESH DEFINITION |
An autophagy related protein which functions as a core subunit of PHOSPHATIDYLINOSITOL 3-KINASE MULTIPROTEIN COMPLEXES. It mediates the formation of phosphatidylinositol 3-phosphate and functions in AUTOPHAGY, where it is required for maturation of the AUTOPHAGOSOME. It also functions in ENDOCYTOSIS and CYTOKINESIS as part of a separate complex. Beclin-1 associates with INTRACELLULAR MEMBRANES and interacts with the PROTO-ONCOGENE PROTEINS C-BCL-2 and BCL-X PROTEIN.
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| MESH UI |
M000613469
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| subClassOf | |
| Semantic type UMLS property | |
| MeSH name |
Beclin-1
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| NDFRT kind |
INGREDIENT_KIND
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| type | |
| tui |
T116
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| NUI |
N0000193060
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| cui |
C4255099
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| MESH DUI |
D000071186
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